Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …
globe. Candida species are among the most common causes of invasive mycotic disease …
Candida auris: Epidemiology, Diagnosis, Pathogenesis, Antifungal Susceptibility, and Infection Control Measures to Combat the Spread of Infections in Healthcare …
S Ahmad, W Alfouzan - Microorganisms, 2021 - mdpi.com
Candida auris, a recently recognized, often multidrug-resistant yeast, has become a
significant fungal pathogen due to its ability to cause invasive infections and outbreaks in …
significant fungal pathogen due to its ability to cause invasive infections and outbreaks in …
Collateral sensitivity counteracts the evolution of antifungal drug resistance in Candida auris
H Carolus, D Sofras, G Boccarella, S Jacobs… - Nature …, 2024 - nature.com
Antifungal drug resistance represents a serious global health threat, necessitating new
treatment strategies. Here we investigated collateral sensitivity (CS), in which resistance to …
treatment strategies. Here we investigated collateral sensitivity (CS), in which resistance to …
[HTML][HTML] The molecular and genetic basis of antifungal resistance in the emerging fungal pathogen Candida auris
Highlights•C. auris exhibits resistance to multiple antifungal agents and represents a public
health threat.•The molecular mechanisms of antifungal resistance observed in C. auris vary …
health threat.•The molecular mechanisms of antifungal resistance observed in C. auris vary …
Review on Antifungal Resistance Mechanisms in the Emerging Pathogen Candida auris
F Chaabane, A Graf, L Jequier, AT Coste - Frontiers in microbiology, 2019 - frontiersin.org
Candida auris is an emerging multi-drug resistant yeast, that causes major issues regarding
patient treatment and surface disinfection in hospitals. Indeed, an important proportion of C …
patient treatment and surface disinfection in hospitals. Indeed, an important proportion of C …
The quiet and underappreciated rise of drug-resistant invasive fungal pathogens
A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …
Genome-wide analysis of experimentally evolved Candida auris reveals multiple novel mechanisms of multidrug resistance
Candida auris is globally recognized as an opportunistic fungal pathogen of high concern,
due to its extensive multidrug resistance (MDR). Still, molecular mechanisms of MDR are …
due to its extensive multidrug resistance (MDR). Still, molecular mechanisms of MDR are …
Candida auris and multidrug resistance: Defining the new normal
SR Lockhart - Fungal Genetics and Biology, 2019 - Elsevier
Candida auris is an emerging species of yeast characterized by colonization of skin,
persistence in the healthcare environment, and antifungal resistance. C. auris was first …
persistence in the healthcare environment, and antifungal resistance. C. auris was first …
On the emergence, spread and resistance of Candida auris: host, pathogen and environmental tipping points
A Chakrabarti, P Sood - Journal of medical microbiology, 2021 - microbiologyresearch.org
Over a decade ago, a multidrug-resistant nosocomial fungus Candida auris emerged
worldwide and has since become a significant challenge for clinicians and microbiologists …
worldwide and has since become a significant challenge for clinicians and microbiologists …
Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris
Candida auris has emerged as a multidrug-resistant pathogen of great clinical concern.
Approximately 90% of clinical C. auris isolates are resistant to fluconazole, the most …
Approximately 90% of clinical C. auris isolates are resistant to fluconazole, the most …