Inflammatory bowel disease (IBD) is a multifactorial disease which arises as a result of the
interaction of genetic, environmental, barrier and microbial factors leading to chronic …

Background Beginning at birth, the microbes in the gut perform essential duties related to
the digestion and metabolism of food, the development and activation of the immune system …

Antibiotics are a modifiable iatrogenic risk factor for the most common human nosocomial
fungal infection, invasive candidiasis, yet the underlying mechanisms remain elusive. We …

Objective Antibiotic use is associated with an increased risk of developing multiple
inflammatory disorders, which in turn are linked to alterations in the intestinal microbiota …

Background We examined the risk of sepsis within 90 days after discharge from a previous
hospital stay by type of antibiotic received during the previous stay. Methods We …

Surgery involving the gastrointestinal tract continues to prove challenging because of the
persistence of unpredictable complications such as anastomotic leakage and life …

INTRODUCTION Although commensal microbes populate our barrier surfaces without
causing obvious disease, they nonetheless modulate host physiology and immunity …

The majority of the epithelial surfaces of our body, and the digestive tract, respiratory and
urogenital systems, are colonized by a vast number of bacteria, archaea, fungi, protozoans …

Chronic high-salt diet-associated renal injury is a key risk factor for the development of
hypertension. However, the mechanism by which salt triggers kidney damage is poorly …

The intestinal microbiome maintains a close relationship with the host immunity. This
connection fosters a health state by direct and indirect mechanisms. Direct influences occur …