Atopic dermatitis (AD) is an important chronic or relapsing inflammatory skin disease that
often precedes asthma and allergic disorders. New insights into the genetics and …

Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine similar to IL-7, whose
gene is located on chromosome 5q22. 1 and it exerts its biological function through the …

Abstract IL-4 and IL-13 are pleiotropic Th2 cytokines produced by a wide variety of different
cell types and responsible for a broad range of biology and functions. Physiologically, Th2 …

Atopic dermatitis is a chronic inflammatory skin disease with a complex pathogenesis, where
changes in skin barrier and imbalance of the immune system are relevant factors. The skin …

BACKGROUND: Staphylococcus aureus heavily colonizes the lesions of patients with atopic
dermatitis (AD) and is known to trigger a worsening of AD. However, the exact mechanism …

Asthma is a chronic airway inflammatory disorder with characteristic symptoms of dyspnea,
wheeze, chest tightness and cough, and physiological abnormalities of variable airway …

Background and Purpose Atopic dermatitis (AD) is a multifactorial skin condition with
complex interactions of innate and adaptive immune responses. There are several existing …

Epithelial cells respond to physicochemical damage with up-regulation of major
histocompatibility complex–like ligands that can activate the cytolytic potential of …

Asthma is an inflammatory disorder of the airways, characterized by infiltration of mast cells,
eosinophils, and Th2-type CD4+ T cells in the airway wall. Airway epithelium constitutes the …

Atopic dermatitis (AD) results from barrier defects combined with modified immune
responses of the innate and the adaptive immune system to exogenous and endogenous …