The dual role of neutrophils in inflammatory bowel diseases
O Wéra, P Lancellotti, C Oury - Journal of clinical medicine, 2016 - mdpi.com
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are
characterised by aberrant immunological responses leading to chronic inflammation without …
characterised by aberrant immunological responses leading to chronic inflammation without …
From flies to men: ROS and the NADPH oxidase in phagocytes
The cellular formation of reactive oxygen species (ROS) represents an evolutionary ancient
antimicrobial defense system against microorganisms. The NADPH oxidases (NOX), which …
antimicrobial defense system against microorganisms. The NADPH oxidases (NOX), which …
[HTML][HTML] NADPH oxidases and ROS signaling in the gastrointestinal tract
Reactive oxygen species (ROS), initially categorized as toxic by-products of aerobic
metabolism, have often been called a double-edged sword. ROS are considered …
metabolism, have often been called a double-edged sword. ROS are considered …
Significance of microbiota in obesity and metabolic diseases and the modulatory potential by medicinal plant and food ingredients
Metabolic syndrome is a cluster of three or more metabolic disorders including insulin
resistance, obesity, and hyperlipidemia. Obesity has become the epidemic of the twenty-first …
resistance, obesity, and hyperlipidemia. Obesity has become the epidemic of the twenty-first …
NOTCH-induced rerouting of endosomal trafficking disables regulatory T cells in vasculitis
The aorta and the large conductive arteries are immunoprivileged tissues and are protected
against inflammatory attack. A breakdown of immunoprivilege leads to autoimmune …
against inflammatory attack. A breakdown of immunoprivilege leads to autoimmune …
Inflammatory consequences of inherited disorders affecting neutrophil function
MC Dinauer - Blood, The Journal of the American Society of …, 2019 - ashpublications.org
Primary immunodeficiencies affecting the function of neutrophils and other phagocytic
leukocytes are notable for an increased susceptibility to bacterial and fungal infections as a …
leukocytes are notable for an increased susceptibility to bacterial and fungal infections as a …
Raising the 'good'oxidants for immune protection
A Dumas, UG Knaus - Frontiers in immunology, 2021 - frontiersin.org
Redox medicine is a new therapeutic concept targeting reactive oxygen species (ROS) and
secondary reaction products for health benefit. The concomitant function of ROS as …
secondary reaction products for health benefit. The concomitant function of ROS as …
Effects of long-term protein restriction on meat quality, muscle amino acids, and amino acid transporters in pigs
J Yin, Y Li, X Zhu, H Han, W Ren, S Chen… - Journal of agricultural …, 2017 - ACS Publications
This study aimed to investigate the long-term effects of protein restriction from piglets to
finishing pigs for 16 weeks on meat quality, muscle amino acids, and amino acid …
finishing pigs for 16 weeks on meat quality, muscle amino acids, and amino acid …
[HTML][HTML] Colitis susceptibility in mice with reactive oxygen species deficiency is mediated by mucus barrier and immune defense defects
Reactive oxygen species (ROS) generated by NADPH oxidases (NOX/DUOX) provide
antimicrobial defense, redox signaling, and gut barrier maintenance. Inactivating NOX …
antimicrobial defense, redox signaling, and gut barrier maintenance. Inactivating NOX …
[HTML][HTML] Intestinal microbiome and metabolome signatures in patients with chronic granulomatous disease
P Chandrasekaran, Y Han, CS Zerbe, T Heller… - Journal of Allergy and …, 2023 - Elsevier
Background Chronic granulomatous disease (CGD) is caused by defects in any 1 of the 6
subunits forming the nicotinamide adenine dinucleotide phosphate oxidase complex 2 …
subunits forming the nicotinamide adenine dinucleotide phosphate oxidase complex 2 …