Understanding immunity in humans to Group A Streptococcus (Strep A) is critical for the
development of successful vaccines to prevent the morbidity and mortality attributed to Strep …

Preclinical antigen discovery, vaccine formulation, and efficacy studies in animal models
have progressed significantly in recent years. There is now a need to move promising …

Coiled coil–forming M proteins of the widespread and potentially deadly bacterial pathogen
Streptococcus pyogenes (strep A) are immunodominant targets of opsonizing antibodies …

The measurement of antibodies to vaccine antigens is crucial for research towards a safe
and effective vaccine for Streptococcus pyogenes (Strep A). We describe the establishment …

Coiled coil-forming M proteins of the widespread and potentially deadly bacterial pathogen
Streptococcus pyogenes (Strep A) are immunodominant targets of opsonizing antibodies …

Design of M protein immunogens to elicit broadly reactive antibodies against Streptococcus
pyogenes Page 1 1 Design of M protein immunogens to elicit broadly reactive antibodies …