[HTML][HTML] Recent advances in exosome-mediated nucleic acid delivery for cancer therapy

Y Zhang, Q Liu, X Zhang, H Huang, S Tang… - Journal of …, 2022 - Springer
Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …

[HTML][HTML] Exosomes, a new star for targeted delivery

H Chen, L Wang, X Zeng, H Schwarz… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing
numerous biological molecules including nucleic acids, proteins and lipids, which are …

Exosome-based smart drug delivery tool for cancer theranostics

R Kar, R Dhar, S Mukherjee, S Nag… - ACS biomaterials …, 2023 - ACS Publications
Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles
derived from the plasma membrane. The main activity of exosomes is cellular …

Extracellular vesicles: A bright star of nanomedicine

P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …

Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance

S Salunkhe, M Basak, D Chitkara, A Mittal - Journal of Controlled …, 2020 - Elsevier
Exosomes are natural nanovesicles excreted by many cells for intercellular communication
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …

Milk exosomes-mediated miR-31-5p delivery accelerates diabetic wound healing through promoting angiogenesis

C Yan, J Chen, C Wang, M Yuan, Y Kang, Z Wu… - Drug …, 2022 - Taylor & Francis
The refractory diabetic wound has remained a worldwide challenge as one of the major
health problems. The impaired angiogenesis phase during diabetic wound healing partly …

Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source

W Meng, C He, Y Hao, L Wang, L Li, G Zhu - Drug delivery, 2020 - Taylor & Francis
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …

Challenges in the development and establishment of exosome-based drug delivery systems

J Wang, D Chen, EA Ho - Journal of Controlled Release, 2021 - Elsevier
Exosomes are extracellular vesicles released from cells and are characterized by a lipid
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …

High-quality milk exosomes as oral drug delivery system

J Zhong, B Xia, S Shan, A Zheng, S Zhang, J Chen… - Biomaterials, 2021 - Elsevier
Many drugs must be administered intravenously instead of oral administration due to their
poor oral bioavailability. The cost of repeated infusion treatment for 6 weeks every year is as …

Exosome-mediated siRNA delivery to suppress postoperative breast cancer metastasis

L Zhao, C Gu, Y Gan, L Shao, H Chen, H Zhu - Journal of Controlled …, 2020 - Elsevier
High recurrence and metastasis of triple-negative breast cancer (TNBC) after operation is a
leading cause of breast cancer related death. The pre-metastatic niche (PMN) is an …