Background Drugs prescribed for psychiatric disorders in adolescence should be studied
very extensively since they can affect developing and thus highly plastic brain differently …

Ketamine has shown promising antidepressant efficacy for adolescent treatment-resistant
depression. However, the potential enduring consequences of ketamine exposure have not …

Drug addiction results in part from maladaptive learning, including the formation of strong
associations between the drug and the circumstances of consumption. However, drug …

This report evaluates the effects of chlordiazepoxide, a benzodiazepine commonly
prescribed to manage anxiety-related disorders in adolescent/pediatric populations, on …

Background Epidemiological reports indicate that mood-related disorders are common in
the adolescent population. The prevalence of juvenile major depressive disorder has …

Background: Preclinical evidence from male subjects indicates that exposure to
psychotropic medications, during early development, results in long-lasting altered …

Background Ketamine (KET) is administered to manage major depression in adolescent
patients. However, the long-term effects of juvenile KET exposure on memory-related tasks …

Corticostriatal circuitry supports flexible reward learning and emotional behavior from the
critical neurodevelopmental stage of adolescence through adulthood. It is still poorly …

Mood-related disorders have a high prevalence among children and adolescents, posing a
public health challenge, given their adverse impact on these young populations. Treatment …

Ketamine, a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist, produces
quick and effective antidepressant results in depressed juvenile and adult individuals. The …