Adaptive therapy is a dynamic cancer treatment protocol that updates (or 'adapts') treatment
decisions in anticipation of evolving tumor dynamics. This broad term encompasses many …

This paper gives a comprehensive review of the application of metaheuristics to optimization
problems in systems biology, mainly focusing on the parameter estimation problem (also …

Uncertainty quantification serves a central role for simulation-based analysis of physical,
engineering, and biological applications using mechanistic models. From a broad …

Up to now in our study of continuous population models we have been assuming that x (t),
the growth rate of population size at time t, depends only on x (t), the population size at the …

Writing a book on smart materials bears a certain semblance to purchasing a high-end
laptop—due to rapid advances in the field, it is tempting to postpone the decision every six …

Modeling and Inverse Problems in the Presence of Uncertainty collects recent research—
including the authors' own substantial projects—on uncertainty propagation and …

Intermittent androgen deprivation therapy (IADT) is an attractive treatment for biochemically
recurrent prostate cancer (PCa), whereby cycling treatment on and off can reduce …

Human breath contains a myriad of endogenous volatile organic compounds (VOCs) which
are reflective of ongoing metabolic or physiological processes. While research into the …

We investigate methods for learning partial differential equation (PDE) models from spatio-
temporal data under biologically realistic levels and forms of noise. Recent progress in …

Most ecosystem functions and related services involve species interactions across trophic
levels, for example, pollination and biological pest control. Despite this, our understanding of …