[HTML][HTML] Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development

L Wang, Y Yan, L Wu, J Peng - Pharmacological Research, 2023 - Elsevier
With changing lifestyles, non-alcoholic fatty liver disease (NAFLD) has become the most
prevalent liver disease worldwide. A substantial increase in the incidence, mortality, and …

[HTML][HTML] Citri Reticulatae Pericarpium (Chenpi): A multi-efficacy pericarp in treating cardiovascular diseases

J Zou, J Wang, W Ye, J Lu, C Li, D Zhang, W Ye… - Biomedicine & …, 2022 - Elsevier
Abstract Citri Reticulatae Pericarpium (CRP) has been utilized as a versatile medicinal herb
with wide cardiovascular benefits in Asian nations for centuries. Accumulating evidence …

Citrus Flavonoids: Biological Activities, Implementation in Skin Health, and Topical Applications: A Review

Z Sebghatollahi, M Ghanadian, P Agarwal… - ACS Food Science & …, 2022 - ACS Publications
Citrus fruits are one of the most popular sources of dietary flavonoids, such as hesperidin,
hesperetin, naringin, naringenin, quercetin, rutin, diosmin, diosmetin, kaempferol, myricetin …

Prognostic and genomic analysis of proteasome 20S subunit alpha (PSMA) family members in breast cancer

CC Chiao, YH Liu, NN Phan, NT An Ton, HDK Ta… - Diagnostics, 2021 - mdpi.com
The complexity of breast cancer includes many interacting biological processes, and
proteasome alpha (PSMA) subunits are reported to be involved in many cancerous …

[HTML][HTML] Prognostic and immune infiltration signatures of proteasome 26S subunit, non-ATPase (PSMD) family genes in breast cancer patients

CC Wu, TJ Kao, HDK Ta, G Anuraga, V Andriani… - Aging (albany …, 2021 - ncbi.nlm.nih.gov
The complexity of breast cancer includes many interacting biological processes that make it
difficult to find appropriate therapeutic treatments. Therefore, identifying potential diagnostic …

[HTML][HTML] Xanthohumol, a prenylated chalcone, regulates lipid metabolism by modulating the LXRα/RXR-ANGPTL3-LPL axis in hepatic cell lines and high-fat diet-fed …

WY Gao, PY Chen, HJ Hsu, JW Liou, CL Wu… - Biomedicine & …, 2024 - Elsevier
Abstract Angiopoietin-like 3 (ANGPTL3) acts as an inhibitor of lipoprotein lipase (LPL),
impeding the breakdown of triglyceride-rich lipoproteins (TGRLs) in circulation. Targeting …

Therapeutic potential of bioactive flavonoids from citrus fruit peels toward obesity and diabetes mellitus

K Lu, YM Yip - Future Pharmacology, 2023 - mdpi.com
Obesity is associated with a significantly increased risk of cardiovascular and metabolic
diseases such as diabetes mellitus. Recently, a growing body of evidence shows that …

Novel insights into the prognosis and immunological value of the SLC35A (solute carrier 35A) family genes in human breast cancer

HDK Ta, DT Minh Xuan, WC Tang, G Anuraga, YC Ni… - Biomedicines, 2021 - mdpi.com
According to statistics 2020, female breast cancer (BRCA) became the most commonly
diagnosed malignancy worldwide. Prognosis of BRCA patients is still poor, especially in …

The citrus flavonoid nobiletin downregulates angiopoietin-like protein 3 (ANGPTL3) expression and exhibits lipid-modulating effects in hepatic cells and adult …

CY Lin, PY Chen, HJ Hsu, WY Gao, MJ Wu… - International Journal of …, 2022 - mdpi.com
Nobiletin, a dietary citrus flavonoid, exerts biological activities against hyperlipidemia,
obesity, and atherosclerotic cardiovascular diseases (ASCVDs). The aim of this study was to …

Selected soybean varieties regulate hepatic LDL-cholesterol homeostasis depending on their glycinin: β-conglycinin ratio

M Rebollo-Hernanz, NA Bringe, E Gonzalez de Mejia - Antioxidants, 2022 - mdpi.com
Clinical studies indicate that the consumption of soybean protein might reduce cholesterol
and LDL levels preventing the development of atherosclerotic cardiovascular diseases …