Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

G Li, E De Clercq - Nature reviews Drug discovery, 2020 - nature.com
Therapeutic options for the 2019 novel coronavirus (2019-nCoV) Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Host-directed antiviral therapy

N Kumar, S Sharma, R Kumar, BN Tripathi… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antiviral drugs have traditionally been developed by directly targeting essential viral
components. However, this strategy often fails due to the rapid generation of drug-resistant …

Overview of recent strategic advances in medicinal chemistry

G Wu, T Zhao, D Kang, J Zhang, Y Song… - Journal of medicinal …, 2019 - ACS Publications
Introducing novel strategies, concepts, and technologies that speed up drug discovery and
the drug development cycle is of great importance both in the highly competitive …

Molecular docking and dynamics studies of Nicotinamide Riboside as a potential multi-target nutraceutical against SARS-CoV-2 entry, replication, and transcription: A …

Z Esam, M Akhavan, A Bekhradnia - Journal of molecular structure, 2022 - Elsevier
Abstract The highly contagious Coronavirus Disease 2019 (COVID-19) caused by Severe
Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which is a newborn infectious …

Inhibitors of nucleotide biosynthesis as candidates for a wide spectrum of antiviral chemotherapy

CS Sepúlveda, CC García, EB Damonte - Microorganisms, 2022 - mdpi.com
Emerging and re-emerging viruses have been a challenge in public health in recent
decades. Host-targeted antivirals (HTA) directed at cellular molecules or pathways involved …

Recent advances on heterocyclic compounds with antiviral properties

A De, S Sarkar, A Majee - Chemistry of Heterocyclic Compounds, 2021 - Springer
In recent years several important viral infections have emerged and antiviral
chemotherapeutic agents are not sufficiently effective in clinic, leading to serious human …

N-Heterocycles as Promising Antiviral Agents: A Comprehensive Overview

G Ahmad, M Sohail, M Bilal, N Rasool, MU Qamar… - Molecules, 2024 - mdpi.com
Viruses are a real threat to every organism at any stage of life leading to extensive infections
and casualties. N-heterocycles can affect the viral life cycle at many points, including viral …

[PDF][PDF] Inhibitors of Nucleotide Biosynthesis as Candidates for a Wide Spectrum of Antiviral Chemotherapy. Microorganisms 2022, 10, 1631

CS Sepúlveda, CC García, EB Damonte - 2022 - academia.edu
Emerging and re-emerging viruses have been a challenge in public health in recent
decades. Host-targeted antivirals (HTA) directed at cellular molecules or pathways involved …

Sistematični pregled in napoved toksičnosti potencialnih učinkovin za zdravljenje COVID-19

M Bajželj - 2020 - repozitorij.uni-lj.si
Abstract Koronavirusno bolezen 2019 (COVID-19) povzroča koronavirus SARS-CoV-2, virus
RNA z ovojnico. Zaradi hitrega širjenja nalezljive bolezni na vseh celinah je Svetovna …

[PDF][PDF] Overview of Recent Strategic Advances in Medicinal Chemistry

OM Denmark - 2019 - researchgate.net
Introducing novel strategies, concepts and technologies that speed up drug discovery and
the drug development cycle is of great importance both in the highly competitive …