Orofacial soft tissue wounds caused by surgery for congenital defects, trauma, or disease
frequently occur leading to complications affecting patients' quality of life. Scarring and …

The main role of salivary glands (SG) is the production and secretion of saliva, in which
aquaporins (AQPs) play a key role by ensuring water flow. The AQPs are transmembrane …

The craniofacial region consists of several different tissue types. These tissues are quite
commonly affected by traumatic/pathologic tissue loss which has so far been traditionally …

Xerostomia or dry mouth are commonly diagnosed in head and neck cancer patients due to
salivary gland (SG) epithelial injury after radiotherapy. Regenerative medicine has fetched …

Mitigation of irradiation injury to salivary glands was previously reported using a cell-free
extract from mouse bone marrow. However, to bring this potential therapy a step closer to …

Radiation therapy is a common treatment for head and neck cancers. However, because of
the presence of nerve structures (brain stem, spinal cord, and brachial plexus), salivary …

In patients with head and neck cancer, irradiation (IR)‐sensitive salivary gland (SG) tissue is
highly prone to damage during radiotherapy (RT). This leads to SG hypofunction and …

Primary cells are an essential tool for in vitro studies and are obtained directly from living
tissues or organs. They closely mimic the physiological state and maintain in vivo functions …

Previous studies demonstrated that salivary gland morphogenesis and differentiation are
enhanced by modification of fibrin hydrogels chemically conjugated to Laminin-1 peptides …

Neuropathic pain is a complex, debilitating disease that results from injury to the
somatosensory nervous system. The presence of systemic chronic inflammation has been …