Despite early and continuous dietary intervention, individuals with early-treated
phenylketonuria (PKU) experience significant neurocognitive sequelae. An area of cognitive …

The aim of this study was to determine the role of executive functions (EFs) in early school
achievement when a variety of potential confounding factors were controlled. Measures of …

Background Autism spectrum disorder is characterized by social communicative deficits with
restricted interests occurring in about 1% of the population. Although its exact cause is not …

Whereas studies of the past 10 years have shown the executive functions (EFs) in adults to
be differentiated into at least three principal components (working memory, inhibition, and …

Objectives To compare the neurocognitive outcomes of patients with phenylketonuria (PKU)
to determine whether decreasing phenylalanine (Phe) levels to< 240 is preferable to the use …

Despite having average intellectual abilities, academic difficulties are relatively common in
children and adolescents with PKU. These academic difficulties may be a function of …

Though the control of blood phenylalanine (Phe) levels is essential for minimizing
impairment in individuals with phenylketonuria (PKU), the empirical basis for the selection of …

Phenylketonuria is an inborn error of phenylalanine (Phe) metabolism diagnosed by
newborn screening and treated early with diet. Although diet prevents intellectual disability …

Background: In untreated patients, phenylketonuria (PKU) results in severe encephalopathy
with mental retardation. A protein-restricted diet is recommended which can be relaxed in …

Objectives The main objective of this study was to investigate the association of
psychological factors and life stressors with quality of life in caregivers of children with PKU …