As populations age worldwide, the burden of valvular heart disease has grown
exponentially, and so has the proportion of affected women. Although rheumatic valve …

Cardiac toxicity is one of the most concerning side effects of anti-cancer therapy. The gain in
life expectancy obtained with anti-cancer therapy can be compromised by increased …

Aims Isolated tricuspid valve surgery (ITVS) is considered to be a high-risk procedure, but in-
hospital mortality is markedly variable. This study sought to develop a dedicated risk score …

Objectives: This study sought to analyze patients with tricuspid regurgitation (TR) diagnosed
in the community setting (Olmsted County) by Doppler echocardiography to define the …

Background: The diagnosis of heart failure may be challenging because symptoms are
rather nonspecific. Elevated left ventricular (LV) filling pressure may be used to confirm the …

Background—Left atrial (LA) structure and function are altered in most heart failure (HF)
patients, but there may be fundamental differences in LA properties between HF with …

Background: Mitral valve (MV) repair is preferred over replacement in clinical guidelines and
is an important determinant of the indication for surgery in degenerative mitral regurgitation …

Valvular heart disease remains common in industrialized countries, because the decrease
in prevalence of rheumatic heart diseases has been accompanied by an increase in that of …

Objectives: We undertook a prospective multicenter single-arm study to evaluate the
feasibility, safety, and efficacy of the MitraClip system (Evalve Inc., Menlo Park, California) …

Background Functional mitral regurgitation (FMR) is a common finding in patients with heart
failure (HF), but its effect on outcome is still uncertain, mainly because in previous studies …