Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases

Y Shi, Y Wang, Q Li, K Liu, J Hou, C Shao… - Nature Reviews …, 2018 - nature.com
Mesenchymal stem cells (MSCs; also referred to as mesenchymal stromal cells) have
attracted much attention for their ability to regulate inflammatory processes. Their therapeutic …

Strategies toward rheumatoid arthritis therapy; the old and the new

M Abbasi, MJ Mousavi, S Jamalzehi… - Journal of cellular …, 2019 - Wiley Online Library
Currently, medications used to treat rheumatoid arthritis (RA) are glucocorticoids (GCs) and
nonsteroidal anti‐inflammatory drugs (NSAIDs), predominantly used for controlling the pain …

Immunomodulation by therapeutic mesenchymal stromal cells (MSC) is triggered through phagocytosis of MSC by monocytic cells

SFH de Witte, F Luk, JM Sierra Parraga, M Gargesha… - stem cells, 2018 - academic.oup.com
Mesenchymal stem or stromal cells (MSC) are under investigation as a potential
immunotherapy. MSC are usually administered via intravenous infusion, after which they are …

Human mesenchymal stem cells-current trends and future prospective

I Ullah, RB Subbarao, GJ Rho - Bioscience reports, 2015 - portlandpress.com
Stem cells are cells specialized cell, capable of renewing themselves through cell division
and can differentiate into multi-lineage cells. These cells are categorized as embryonic stem …

Same or not the same? Comparison of adipose tissue-derived versus bone marrow-derived mesenchymal stem and stromal cells

M Strioga, S Viswanathan, A Darinskas… - Stem cells and …, 2012 - liebertpub.com
Mesenchymal stem/stromal cells (MSCs) comprise a heterogeneous population of cells with
multilineage differentiation potential, the ability to modulate oxidative stress, and secrete …

Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis

K Akiyama, C Chen, DD Wang, X Xu, C Qu, T Yamaza… - Cell stem cell, 2012 - cell.com
Systemic infusion of bone marrow mesenchymal stem cells (BMMSCs) yields therapeutic
benefit for a variety of autoimmune diseases, but the underlying mechanisms are poorly …

Immunosuppressive properties of mesenchymal stem cells: advances and applications

MP De Miguel, S Fuentes-Julian… - Current molecular …, 2012 - ingentaconnect.com
Mesenchymal stem cells (MSCs) have been isolated from a variety of tissues, such as bone
marrow, skeletal muscle, dental pulp, bone, umbilical cord and adipose tissue. MSCs are …

Mesenchymal stem cells in health and disease

A Uccelli, L Moretta, V Pistoia - Nature reviews immunology, 2008 - nature.com
Mesenchymal stem cells (MSCs) are a heterogeneous subset of stromal stem cells that can
be isolated from many adult tissues. They can differentiate into cells of the mesodermal …

MSCs: delivery routes and engraftment, cell‐targeting strategies, and immune modulation

TJ Kean, P Lin, AI Caplan, JE Dennis - Stem cells international, 2013 - Wiley Online Library
Mesenchymal stem cells (MSCs) are currently being widely investigated both in the lab and
in clinical trials for multiple disease states. The differentiation, trophic, and …

How mesenchymal stem cells interact with tissue immune responses

Y Shi, J Su, AI Roberts, P Shou, AB Rabson… - Trends in immunology, 2012 - cell.com
Mesenchymal stem cells (MSCs), also called multipotent mesenchymal stromal cells, exist in
almost all tissues and are a key cell source for tissue repair and regeneration. Under …