Transcription factors in cartilage homeostasis and osteoarthritis

M Neefjes, APM van Caam, PM van der Kraan - Biology, 2020 - mdpi.com
Osteoarthritis (OA) is the most common degenerative joint disease, and it is characterized by
articular cartilage loss. In part, OA is caused by aberrant anabolic and catabolic activities of …

Lineage-specific differences and regulatory networks governing human chondrocyte development

D Richard, S Pregizer, D Venkatasubramanian… - Elife, 2023 - elifesciences.org
To address large gaps in our understanding of the molecular regulation of articular and
growth plate cartilage development in humans, we used our directed differentiation …

Immune dysfunction and multiple treatment modalities for the SARS-CoV-2 pandemic: races of uncontrolled running sweat?

A Kothari, V Singh, UK Nath, S Kumar, V Rai… - Biology, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic
threat with more than 11.8 million confirmed cases and more than 0.5 million deaths as of 3 …

A Multimodal Molecular View of Human Cartilage Development

D Venkatasubramanian - 2024 - dash.harvard.edu
The skeletal system is the foundation of human mobility. Human joint development and
function relies on the proper specification and differentiation of hyaline cartilage, including …

[图书][B] Biological Rhythms in the Intervertebral Disc: Implications for Homeostasis and Degeneration

HL Morris - 2022 - search.proquest.com
Biological rhythms temporally coordinate physiological and behavioural processes and are
observed across taxa. Perhaps the best-known biological rhythm is the circadian rhythm …