MicroRNAs in extracellular vesicles: sorting mechanisms, diagnostic value, isolation, and detection technology

D Xu, K Di, B Fan, J Wu, X Gu, Y Sun… - … in Bioengineering and …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of short, single-stranded, noncoding RNAs, with a length
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …

Preeclampsia and fetal growth restriction as risk factors of future maternal cardiovascular disease—A review

S Sławek-Szmyt, K Kawka-Paciorkowska… - Journal of Clinical …, 2022 - mdpi.com
Cardiovascular diseases (CVDs) remain the leading cause of death in women worldwide.
Although traditional risk factors increase later-life CVD, pregnancy-associated complications …

Small extracellular vesicles from pregnant women with maternal supraphysiological hypercholesterolemia impair endothelial cell function in vitro

S Contreras-Duarte, R Escalona-Rivano, C Cantin… - Vascular …, 2023 - Elsevier
Maternal physiological hypercholesterolemia MPH, maternal total cholesterol (TC) levels at
term of pregnancy≤ 280 mg/dL) occurs to assure fetal development. Maternal …

Placental extracellular vesicles promote cardiomyocyte maturation and fetal heart development

MJ Jeyarajah, VS Patterson, G Jaju Bhattad… - Communications …, 2024 - nature.com
Congenital heart defects are leading causes of neonatal mortality and are often associated
with placental abnormalities, but mechanisms linking placenta and heart development are …

Exploring the role of exosomal MicroRNAs as potential biomarkers in preeclampsia

Y Shan, B Hou, J Wang, A Chen, S Liu - Frontiers in Immunology, 2024 - frontiersin.org
The complex pathogenesis of preeclampsia (PE), a significant contributor to maternal and
neonatal mortality globally, is poorly understood despite substantial research. This review …

基于外泌体多miRNA 表达水平构建的子痫前期风险预测模型效能分析.

邓乾葆, 张忠霞, 王茹, 许琳, 罗书 - Tianjin Medical Journal, 2024 - search.ebscohost.com
目的探讨基于多个外泌体微小RNA (miRNA) 表达水平构建子痫前期(PE) 风险模型的可行性,
并验证其对PE 的预测效能. 方法选择2019 年6 月—2021 年12 月建档且孕周≤ 20 周的孕妇1 …

Decreased Extracellular Vesicle Vasorin in Severe Preeclampsia Plasma Mediates Endothelial Dysfunction

S Murugesan, DR Addis, H Hussey, MF Powell… - bioRxiv, 2024 - biorxiv.org
Background Preeclampsia (PE) is a serious pregnancy complication affecting 5-8% of
pregnancies globally. It is a leading cause of maternal and neonatal morbidity and mortality …

Molecular Docking and Intracellular Translocation of Extracellular Vesicles for Efficient Drug Delivery

Y Matsuzaka, R Yashiro - International Journal of Molecular Sciences, 2022 - mdpi.com
Extracellular vesicles (EVs), including exosomes, mediate intercellular communication by
delivering their contents, such as nucleic acids, proteins, and lipids, to distant target cells …