Applications of high‐resolution magic angle spinning MRS in biomedical studies I—cell line and animal models

E Kaebisch, TL Fuss, LA Vandergrift… - NMR in …, 2017 - Wiley Online Library
High‐resolution magic angle spinning (HRMAS) MRS allows for direct measurements of non‐
liquid tissue and cell specimens to present valuable insights into the cellular metabolisms of …

[HTML][HTML] Histopathological effects of ultraviolet radiation exposure on the ocular structures in animal studies–literature review

N Hamba, A Gerbi, S Tesfaye - Translational Research in Anatomy, 2021 - Elsevier
The transparent anterior segment of the human eye (cornea and lens), as well as neural
retina, are the principal target of UV radiation for both acute and long-term exposure. The …

Metabolomic composition of normal aged and cataractous human lenses

YP Tsentalovich, TD Verkhovod, VV Yanshole… - Experimental eye …, 2015 - Elsevier
Quantitative metabolomic profiles of normal and cataractous human lenses were obtained
with the combined use of high-frequency nuclear magnetic resonance (NMR) and high …

Metabolomics of the rat lens: A combined LC-MS and NMR study

VV Yanshole, OA Snytnikova, AS Kiryutin… - Experimental eye …, 2014 - Elsevier
This work is the first comprehensive report on the quantitative metabolomic composition of
the rat lens. Quantitative metabolomic profiles of lenses were acquired with the combined …

Aggregation of α-crystallins in kynurenic acid-sensitized UVA photolysis under anaerobic conditions

PS Sherin, EA Zelentsova, ED Sormacheva… - Physical Chemistry …, 2016 - pubs.rsc.org
The reactions of photoexcited kynurenic acid (KNA) with bovine α-crystallins under
anaerobic conditions proceed via the electron transfer from tryptophan (Trp) and tyrosine …

[HTML][HTML] Involvement of inositol biosynthesis and nitric oxide in the mediation of UV-B induced oxidative stress

DI Lytvyn, C Raynaud, AI Yemets… - Frontiers in Plant …, 2016 - frontiersin.org
The involvement of NO-signaling in ultraviolet B (UV-B) induced oxidative stress (OS) in
plants is an open question. Inositol biosynthesis contributes to numerous cellular functions …

High-resolution magic angle spinning—enabling applications of NMR spectroscopy to semi-solid phases

WP Power - Annual reports on NMR spectroscopy, 2011 - Elsevier
High-resolution magic angle spinning (HRMAS) is the combined application of high-
resolution NMR experiments with dipolar-and susceptibility-reducing sample rotation to …

Effect of UVA and UVB Irradiation on the Metabolic Profile of Rabbit Cornea and Lens Analysed by HR-MAS 1H NMR Spectroscopy

MB Tessem, A Midelfart, J Čejková, TF Bathen - Ophthalmic Research, 2006 - karger.com
Purpose: The aim of the study was to investigate the metabolic profiles of intact rabbit
corneas and lenses exposed to UVA and UVB radiation by using high-resolution (HR) magic …

Metabonomics–a new approach in ophthalmology

A Midelfart - Acta Ophthalmologica, 2009 - Wiley Online Library
Metabonomics is a new technology providing broad information about dynamic metabolic
responses in living systems to pathophysiological stimuli or genetic modification. Nuclear …

[HTML][HTML] Protective effect of the thioltransferase gene on in vivo UVR-300 nm–induced cataract

M Kronschläger, K Galichanin, J Ekström… - … & Visual Science, 2012 - tvst.arvojournals.org
Purpose.: To determine the protection factor (PF) for glutaredoxin-1 (Grx1) with regard to
UVR-induced cataract by comparison of in vivo ultraviolet radiation (UVR) lens toxicity …