Development of testes in the mammalian embryo requires the formation and assembly of
several cell types that allow these organs to achieve their roles in male reproduction and …

Imaging of lymphangiogenesis and angiogenesis requires robust and unambiguous
markers of lymphatic and blood vessels. Although much progress has been made in recent …

In the last decade, much data has been generated concerning the molecular mechanisms of
lymphangiogenesis and its significance in pathological conditions. This was mainly due to …

Testicular germ cell cancers in young adult men derive from a precursor lesion called
carcinoma in situ (CIS) of the testis. CIS cells were suggested to arise from primordial germ …

Testicular germ cell tumors (TGCT) are the most common malignancy in young men. While
most TGCT are potentially curable, approximately 5% of patients with TGCT may develop …

Pula B, Jethon A, Piotrowska A, Gomulkiewicz A, Owczarek T, Calik J, Wojnar A, Witkiewicz
W, Rys J, Ugorski M, Dziegiel P & Podhorska‐Okolow M (2011) Histopathology 59, 1249 …

This review focuses on the molecular characteristics and development of rare malignant
ovarian germ cell tumors (mOGCTs). We provide an overview of the genomic aberrations …

Background: Testicular germ cell tumours of young adults, seminoma or non-seminomas,
are preceded by a pre-invasive precursor, carcinoma in situ (CIS), understood to arise …

Cryptorchidism in males constitutes a notable risk factor for both infertility and testicular
cancer. Infertility in adulthood is closely linked to the germ cell status in childhood …

This concise review summarises tissue and serum markers useful for differential diagnosis
of germ cell tumours (GCT), with focus on the most common testicular GCT (TGCT). GCT are …