Pericyte control of blood flow across microvascular zones in the central nervous system
DA Hartmann, V Coelho-Santos… - Annual review of …, 2022 - annualreviews.org
The vast majority of the brain's vascular length is composed of capillaries, where our
understanding of blood flow control remains incomplete. This review synthesizes current …
understanding of blood flow control remains incomplete. This review synthesizes current …
Astrocyte calcium signaling: the third wave
N Bazargani, D Attwell - Nature neuroscience, 2016 - nature.com
The discovery that transient elevations of calcium concentration occur in astrocytes, and
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
G-protein-coupled receptors in astrocyte–neuron communication
Astrocytes, a major type of glial cell, are known to play key supportive roles in brain function,
contributing to ion and neurotransmitter homeostasis, maintaining the blood–brain barrier …
contributing to ion and neurotransmitter homeostasis, maintaining the blood–brain barrier …
New functions of Müller cells
A Reichenbach, A Bringmann - Glia, 2013 - Wiley Online Library
Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and
metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate …
metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate …
Astrocyte regulation of blood flow in the brain
BA MacVicar, EA Newman - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Neuronal activity results in increased blood flow in the brain, a response named functional
hyperemia. Astrocytes play an important role in mediating this response. Neurotransmitters …
hyperemia. Astrocytes play an important role in mediating this response. Neurotransmitters …
Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases
Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …
A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo
The purinergic transmitter ATP (adenosine 5′-triphosphate) plays an essential role in both
the central and peripheral nervous systems, and the ability to directly measure extracellular …
the central and peripheral nervous systems, and the ability to directly measure extracellular …
Age‐related macular degeneration: new paradigms for treatment and management of AMD
LF Hernández-Zimbrón… - Oxidative medicine …, 2018 - Wiley Online Library
Age‐related macular degeneration (AMD) is a well‐characterized and extensively studied
disease. It is currently considered the leading cause of visual disability among patients over …
disease. It is currently considered the leading cause of visual disability among patients over …
Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma
Y Miao, GL Zhao, S Cheng, Z Wang, XL Yang - Progress in retinal and eye …, 2023 - Elsevier
Elevation of intraocular pressure (IOP) is a major risk factor for neurodegeneration in
glaucoma. Glial cells, which play an important role in normal functioning of retinal neurons …
glaucoma. Glial cells, which play an important role in normal functioning of retinal neurons …
ATP synthesis and storage
Since 1929, when it was discovered that ATP is a substrate for muscle contraction, the
knowledge about this purine nucleotide has been greatly expanded. Many aspects of cell …
knowledge about this purine nucleotide has been greatly expanded. Many aspects of cell …