Mesenchymal stromal cells (MSCs), also known as mesenchymal stem cells, have been
intensely investigated for clinical applications within the last decades. However, the majority …

Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …

Tumor metastasis is a hallmark of cancer. The communication between cancer-derived
exosomes and stroma plays an irreplaceable role in facilitating pre-metastatic niche …

The optimal treatment for complex fractures and large bone defects is an important unsolved
issue in orthopedics and related specialties. Approximately 5–10% of fractures fail to heal …

Mesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells
that have been isolated from a variety of tissues, and possess multipotent differentiation …

Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered
in bone marrow, are multipotent cells capable of differentiating into mature cells of several …

Adipose/fat tissue provides an abundant source of stromal vascular fraction (SVF) cells for
immediate administration and can also give rise to a substantial number of cultured …

Background As one of the main functional forms of mesenchymal stem cells (MSCs), MSC-
derived extracellular vesicles (MSC-EVs) have shown an alternative therapeutic option in …

Mesenchymal stem cells (MSC) are known to facilitate healing of ischemic tissue related
diseases through proangiogenic secretory proteins. Recent studies further show that MSC …

Cell-based therapies have the potential to revolutionize current treatments for diseases with
high prevalence and related economic and social burden. Unfortunately, clinical trials have …