Nigella sativa L. (Black Cumin): A Promising Natural Remedy for Wide Range of Illnesses

EM Yimer, KB Tuem, A Karim… - Evidence‐Based …, 2019 - Wiley Online Library
The seed of Nigella sativa (N. sativa) has been used in different civilization around the world
for centuries to treat various animal and human ailments. So far, numerous studies …

Feeling nature's PAINS: natural products, natural product drugs, and pan assay interference compounds (PAINS)

JB Baell - Journal of natural products, 2016 - ACS Publications
We have previously reported on classes of compounds that can interfere with bioassays via
a number of different mechanisms and termed such compounds Pan Assay INterference …

Thymoquinone and its therapeutic potentials

S Darakhshan, AB Pour, AH Colagar… - Pharmacological …, 2015 - Elsevier
Herbal medicine has attracted great attention in the recent years and is increasingly used as
alternatives to chemical drugs. Several lines of evidence support the positive impact of …

Spices for prevention and treatment of cancers

J Zheng, Y Zhou, Y Li, DP Xu, S Li, HB Li - Nutrients, 2016 - mdpi.com
Spices have been widely used as food flavorings and folk medicines for thousands of years.
Numerous studies have documented the antioxidant, anti-inflammatory and …

Dietary natural products for prevention and treatment of breast cancer

Y Li, S Li, X Meng, RY Gan, JJ Zhang, HB Li - Nutrients, 2017 - mdpi.com
Breast cancer is the most common cancer among females worldwide. Several
epidemiological studies suggested the inverse correlation between the intake of vegetables …

Targeting transcription factor STAT3 for cancer prevention and therapy

EZP Chai, MK Shanmugam, F Arfuso… - Pharmacology & …, 2016 - Elsevier
Abstract Signal Transducers and Activators of Transcription (STATs) comprise an important
class of transcription factors that have been implicated in a wide variety of essential cellular …

Immunomodulatory and anti-inflammatory action of Nigella sativa and thymoquinone: A comprehensive review

AF Majdalawieh, MW Fayyad - International immunopharmacology, 2015 - Elsevier
Many herbal products are now used as remedies to treat various infectious and non-
infectious conditions. Even though the use of herbs and natural products is much more …

The biosynthesis of thymol, carvacrol, and thymohydroquinone in Lamiaceae proceeds via cytochrome P450s and a short-chain dehydrogenase

ST Krause, P Liao, C Crocoll… - Proceedings of the …, 2021 - National Acad Sciences
Thymol and carvacrol are phenolic monoterpenes found in thyme, oregano, and several
other species of the Lamiaceae. Long valued for their smell and taste, these substances also …

Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa

AF Majdalawieh, MW Fayyad… - Critical reviews in food …, 2017 - Taylor & Francis
Over the past two decades, studies have documented the wide-range anti-cancer effects of
Nigella sativa, known as black seed or black cumin. Thymoquinone (TQ), its major active …

[HTML][HTML] The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies

M Butnariu, C Quispe, J Herrera-Bravo, P Helon… - Biomedicine & …, 2022 - Elsevier
Thymoquinone (TQ) is a secondary metabolite found in abundance in very few plant species
including Nigella sativa L., Monarda fistulosa L., Thymus vulgaris L. and Satureja montana …