The novel corona virus disease has shaken the entire world with its deadly effects and rapid
transmission rates, posing a significant challenge to the healthcare authorities to develop …

Suppression of the immune system has been constantly reported in the last years as a
classical side effect of opioid drugs. Most of the studies on the immunological properties of …

In patients with cancer, opioids are principally used for the management of acute surgical
and chronic cancer‐related pain. However, opioids have many non‐analgesic effects …

Despite the increasing clinical use of transdermal buprenorphine, questions have persisted
about the possibility of a ceiling effect for analgesia, its combination with other μ‐opioid …

Written for practitioners in the field, this critically acclaimed bestseller provides authoritative
information focused on the investigation of drug-related deaths and practical approaches to …

Opioid compounds such as morphine produce powerful analgesia that is effective in treating
various types of pain. In addition to their therapeutic efficacy, opioids can produce several …

Despite impressive advances in biomedical research, few noteworthy breakthroughs have
been made in the treatment of sepsis during the past several decades. This stalemate is …

Background: Opioid abuse has increased at an alarming rate. However, available evidence
suggests a wide variance in the use of opioids, as documented by different medical …

Buprenorphine is an opioid that has a complex and unique pharmacology which provides
some advantages over other potent mu agonists. We review 12 reasons for considering …

Buprenorphine was not used widely in clinical practice over many years, mainly due to
analgesic potency and clinical safety concerns based on misinterpreted animal data …