Certain clinical features of schizophrenia, such as working memory disturbances, appear to
emerge from altered gamma oscillatory activity in the prefrontal cortex (PFC). Given the …

Hippocampal area CA2 has several features that distinguish it from CA1 and CA3, including
a unique gene expression profile, failure to display long-term potentiation and relative …

The hippocampus is critical for encoding declarative memory, our repository of knowledge of
who, what, where and when. Mnemonic information is processed in the hippocampus …

Impairments in certain cognitive functions, such as working memory, are core features of
schizophrenia. Convergent findings indicate that a deficiency in signalling through the TrkB …

To date, there has been little investigation of the neurobiological basis of emotion
processing abnormalities in psychiatric populations. We have previously discussed two …

Despite a hundred years' research, the neuropathology of schizophrenia remains obscure.
However, neither can the null hypothesis be sustained—that it is afunctional'psychosis, a …

Cognitive deficits in schizophrenia remain an unmet clinical need. Improved understanding
of the neuro-and psychopathology of these deficits depends on the availability of carefully …

The concept of cognitive map has been proposed as a way to organize our experiences and
guide behavior across all domains of cognition. The hippocampus has been identified as the …

Background: Youths with bipolar disorder are ideal for studying illness pathophysiology
given their early presentation, lack of extended treatment, and high genetic loading. Adult …

A core component to corticolimbic circuitry is the GABAergic interneuron. Neuroanatomic
studies conducted over the past century have demonstrated several subtypes of interneuron …