Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

The spatial regulation of protein translation is an efficient way to create functional and
structural asymmetries in cells. Recent research has furthered our understanding of how …

Abstract mRNA is packaged into ribonucleoprotein particles called mRNPs. A multitude of
RNA-binding proteins as well as a host of associated proteins participate in the fate of …

MG and SRB aptamers, which are short RNA sequences originally selected only for binding
to malachite green or sulforhodamine B, can greatly enhance the fluorescence of normally …

Cells use molecular motors, such as myosins, to move, position and segregate their
organelles. Class V myosins possess biochemical and structural properties that should …

The myosin family of actin filament-based molecular motors consists of at least 20
structurally and functionally distinct classes. The human genome contains nearly 40 myosin …

Abstract mRNA localization is a common mechanism for targeting proteins to regions of the
cell where they are required. It has an essential role in localizing cytoplasmic determinants …

Cytoplasmic messenger RNA localization is a key post-transcriptional mechanism of
establishing spatially restricted protein synthesis. The characterization of cis-acting signals …

The yeast two-hybrid system pioneered the field of in vivo protein-protein interaction
methods and undisputedly gave rise to a palette of ingenious techniques that are constantly …

Chicken embryo fibroblasts (CEFs) localize β-actin mRNA to their lamellae, a process
important for the maintenance of cell polarity and motility. The localization of β-actin mRNA …