Articular cartilage (AC) plays an unquestionable role in joint movements but unfortunately
the healing capacity is restricted due to its avascular and acellular nature. While cartilage …

Calcium phosphate (CaP)‐based ceramics are the most widely applied synthetic
biomaterials for repair and regeneration of damaged and diseased bone. CaP bioactivity is …

Multiple physical cues such as hierarchical microstructures, topography, and stiffness
influence cell fate during tissue regeneration. Yet, introducing multiple physical cues to the …

The mechanisms underlying the osteogenic differentiation of human bone marrow
mesenchymal stem cells (hBMSCs) remain unclear. In the present study, we aimed to …

The coated porous section of stem surface is initially filled with callus that undergoes
osseointegration process, which develops a bond between stem and bone, lessens the …

While it is well established that an adequate blood supply is critical to successful bone
regeneration, it remains poorly understood how progenitor cell fate is affected by the altered …

Fracture healing is a very complex physiological process involving multiple events at
different temporal and spatial scales, such as cell migration and tissue differentiation, in …

There is increased interest in recapitulating aspects of development when designing new
tissue engineering strategies. Long bones and their epiphyses are formed through …

Abstract Zinc oxide nanoparticles (ZnO-NPs) have been widely used in engineering and
biomedicine. However, their adverse pathological effects and mechanisms, especially the …

Objective: Computational model of bone healing can replace animal experiments to study
the parameters affecting the bone healing process, thus reducing the damage to …