Emergent simplicities in the living histories of individual cells
Organisms maintain the status quo, holding key physiological variables constant to within an
acceptable tolerance, and yet adapt with precision and plasticity to dynamic changes in …
acceptable tolerance, and yet adapt with precision and plasticity to dynamic changes in …
Optimal harvesting policy for biological resources with uncertain heterogeneity for application in fisheries management
H Yoshioka - Natural Resource Modeling, 2024 - Wiley Online Library
Conventional harvesting problems for natural resources often assume physiological
homogeneity of the body length/weight among individuals. However, such assumptions …
homogeneity of the body length/weight among individuals. However, such assumptions …
Optimal control of ribosome population for gene expression under periodic nutrient intake
C Soubrier, E Foxall, L Ciandrini… - Journal of the Royal …, 2024 - royalsocietypublishing.org
Translation of proteins is a fundamental part of gene expression that is mediated by
ribosomes. As ribosomes significantly contribute to both cellular mass and energy …
ribosomes. As ribosomes significantly contribute to both cellular mass and energy …
Optimisation of gene expression noise for cellular persistence against lethal events
Bacterial cell persistence, crucial for survival under adverse conditions like antibiotic
exposure, is intrinsically linked to stochastic fluctuations in gene expression. Certain genes …
exposure, is intrinsically linked to stochastic fluctuations in gene expression. Certain genes …
Revisiting moment-closure methods with heterogeneous multiscale population models
D Lunz, JF Bonnans, J Ruess - Mathematical Biosciences, 2022 - Elsevier
Stochastic chemical kinetics at the single-cell level give rise to heterogeneous populations
of cells even when all individuals are genetically identical. This heterogeneity can lead to …
of cells even when all individuals are genetically identical. This heterogeneity can lead to …
The Meaning and Accuracy of the Improving Functions in the Solution of the CBQR by Krotov's Method
I Halperin - Mathematics, 2024 - mdpi.com
A new solution to the continuous-time bilinear quadratic regulator optimal control problem
(CBQR) was recently developed using Krotov's Method. This paper provides two theoretical …
(CBQR) was recently developed using Krotov's Method. This paper provides two theoretical …
Modeling and Optimal Control of a Two-Species Bioproducing Microbial Consortium
D Lunz, J Frédéric Bonnans - SIAM Journal on Applied Mathematics, 2023 - SIAM
Motivated by recent laboratory experiments, we study microbial populations with light-
inducible genetic differentiation that generates a two-species microbial consortium relevant …
inducible genetic differentiation that generates a two-species microbial consortium relevant …
Hysteresis and noise floor in gene expression optimised for persistence against lethal events
Bacterial cell persistence, crucial for survival under adverse conditions like antibiotic
exposure, is intrinsically linked to stochastic fluctuations in gene expression. Certain genes …
exposure, is intrinsically linked to stochastic fluctuations in gene expression. Certain genes …
[PDF][PDF] Revisiting moment closure methods with population models
D Lunz, JF Bonnans, J Ruess - 2021 - researchgate.net
Stochastic chemical kinetics at the single-cell level give rise to heterogeneous populations
of cells even when all individuals are genetically identical. This heterogeneity can lead to …
of cells even when all individuals are genetically identical. This heterogeneity can lead to …