Recent studies have identified the importance of proinflammatory mediators in the
development and progression of heart failure. The growing appreciation of the …

Heart failure (HF) is characterized by the elaboration of a portfolio of pro-inflammatory
cytokines and inflammatory mediators that are considered to contribute to disease …

BACKGROUND: Myocardial dysfunction has been associated with inflammation and
cytokine modulation. OBJECTIVES: The study objective was to understand the role of …

Recent studies have identified the importance of proinflammatory mediators in regulating
cardiac structure in health and disease. Recent studies suggest that cytokines that are …

Objectives: This study sought to compare the effectiveness and safety of an angiotensin
converting enzyme inhibitor (ACE-I)(lisinopril) vs. an angiotensin receptor blocker …

Recent studies have identified the importance of proinflammatory mediators in the
development and progression of chronic heart failure (CHF). The growing appreciation of …

The cardiac fibroblast (CF) has historically been thought of as a quiescent cell of the heart,
passively maintaining the extracellular environment for the cardiomyocytes (CM), the …

Objective: To investigate evidence for the interplay between cytokines, angiotensin II and
nNOS in the paraventricular nucleus (PVN), for regulating sympathetic outflow in a rat model …

Atrial fibrillation (AF) and heart failure (HF) are two cardiovascular diseases with an
increasing prevalence worldwide. These conditions share common pathophysiologiesand …

One of the major conceptual advances in our understanding of the pathogenesis of heart
failure has been the insight that heart failure may progress as the result of the sustained …