Understanding of sarcopenia: from definition to therapeutic strategies
JW Kim, R Kim, H Choi, SJ Lee, GU Bae - Archives of pharmacal research, 2021 - Springer
Sarcopenia refers to the gradual loss of skeletal muscle mass and function along with aging
and is a social burden due to growing healthcare cost associated with a super-aging society …
and is a social burden due to growing healthcare cost associated with a super-aging society …
Malnutrition, frailty, and sarcopenia in patients with cirrhosis: 2021 practice guidance by the American Association for the Study of Liver Diseases
This is the first American Association for the Study of Liver Diseases (AASLD) practice
guidance on the management of malnutrition, frailty, and sarcopenia in patients with …
guidance on the management of malnutrition, frailty, and sarcopenia in patients with …
Liver transplantation in the patient with physical frailty
Frailty is a decline in functional reserve across multiple physiological systems. A key
component of frailty is sarcopenia, which denotes a loss of skeletal muscle mass and …
component of frailty is sarcopenia, which denotes a loss of skeletal muscle mass and …
[HTML][HTML] Side effects of amino acid supplements
M Holeček - Physiological research, 2022 - ncbi.nlm.nih.gov
The aim of the article is to examine side effects of increased dietary intake of amino acids,
which are commonly used as a dietary supplement. In addition to toxicity, mutagenicity and …
which are commonly used as a dietary supplement. In addition to toxicity, mutagenicity and …
Adaptive exhaustion during prolonged intermittent hypoxia causes dysregulated skeletal muscle protein homeostasis
AH Attaway, A Bellar, S Mishra… - The Journal of …, 2023 - Wiley Online Library
Nocturnal hypoxaemia, which is common in chronic obstructive pulmonary disease (COPD)
patients, is associated with skeletal muscle loss or sarcopenia, which contributes to adverse …
patients, is associated with skeletal muscle loss or sarcopenia, which contributes to adverse …
[HTML][HTML] Alcohol and skeletal muscle in health and disease
L Simon, BL Bourgeois, PE Molina - Alcohol Research: Current …, 2023 - ncbi.nlm.nih.gov
PURPOSE Alcohol-related myopathy is one of the earliest alcohol-associated pathological
tissue changes that is progressively exacerbated by cumulative long-term alcohol misuse …
tissue changes that is progressively exacerbated by cumulative long-term alcohol misuse …
[HTML][HTML] Metabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence
Ammonia is a cytotoxic metabolite with pleiotropic molecular and metabolic effects, including
senescence induction. During dysregulated ammonia metabolism, which occurs in chronic …
senescence induction. During dysregulated ammonia metabolism, which occurs in chronic …
Dysregulated cellular redox status during hyperammonemia causes mitochondrial dysfunction and senescence by inhibiting sirtuin‐mediated deacetylation
Perturbed metabolism of ammonia, an endogenous cytotoxin, causes mitochondrial
dysfunction, reduced NAD+/NADH (redox) ratio, and postmitotic senescence. Sirtuins are …
dysfunction, reduced NAD+/NADH (redox) ratio, and postmitotic senescence. Sirtuins are …
Acute binge alcohol alters whole body metabolism and the time-dependent expression of skeletal muscle-specific metabolic markers for multiple days in mice
AL Tice, JA Laudato, DA Fadool… - American Journal …, 2022 - journals.physiology.org
Alcohol is a myotoxin that disrupts skeletal muscle function and metabolism, but specific
metabolic alternations following a binge and the time course of recovery remain undefined …
metabolic alternations following a binge and the time course of recovery remain undefined …
In utero exposure to mercury is associated with increased susceptibility to liver injury and inflammation in childhood
Malnutrition, Frailty, and Sarcopenia in Patients With Cirrh... : Hepatology Malnutrition, Frailty,
and Sarcopenia in Patients With Cirrhosis: 2021 Practice Guidance by the American Association …
and Sarcopenia in Patients With Cirrhosis: 2021 Practice Guidance by the American Association …