Molecular mechanisms and consequences of mitochondrial permeability transition
Mitochondrial permeability transition (mPT) is a phenomenon that abruptly causes the flux of
low molecular weight solutes (molecular weight up to 1,500) across the generally …
low molecular weight solutes (molecular weight up to 1,500) across the generally …
Bioactive peptides: Synthesis, sources, applications, and proposed mechanisms of action
M Akbarian, A Khani, S Eghbalpour… - International journal of …, 2022 - mdpi.com
Bioactive peptides are a group of biological molecules that are normally buried in the
structure of parent proteins and become active after the cleavage of the proteins. Another …
structure of parent proteins and become active after the cleavage of the proteins. Another …
Mitochondrial pores at the crossroad between cell death and inflammatory signaling
Mitochondria are cellular organelles with a major role in many cellular processes, including
not only energy production, metabolism, and calcium homeostasis but also regulated cell …
not only energy production, metabolism, and calcium homeostasis but also regulated cell …
Instability challenges and stabilization strategies of pharmaceutical proteins
M Akbarian, SH Chen - Pharmaceutics, 2022 - mdpi.com
Maintaining the structure of protein and peptide drugs has become one of the most important
goals of scientists in recent decades. Cold and thermal denaturation conditions …
goals of scientists in recent decades. Cold and thermal denaturation conditions …
Ion channels of the sarcolemma and intracellular organelles in Duchenne muscular dystrophy: a role in the dysregulation of ion homeostasis and a possible target for …
MV Dubinin, KN Belosludtsev - International Journal of Molecular …, 2023 - mdpi.com
Duchenne muscular dystrophy (DMD) is caused by the absence of the dystrophin protein
and a properly functioning dystrophin-associated protein complex (DAPC) in muscle cells …
and a properly functioning dystrophin-associated protein complex (DAPC) in muscle cells …
Histological methods to assess skeletal muscle degeneration and regeneration in Duchenne muscular dystrophy
N Dubuisson, R Versele, C Planchon… - International journal of …, 2022 - mdpi.com
Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of
function of the protein dystrophin. This protein contributes to the stabilisation of striated cells …
function of the protein dystrophin. This protein contributes to the stabilisation of striated cells …
The effect of uridine on the state of skeletal muscles and the functioning of mitochondria in Duchenne dystrophy
MV Dubinin, VS Starinets, NV Belosludtseva… - International Journal of …, 2022 - mdpi.com
Duchenne muscular dystrophy is caused by the loss of functional dystrophin that secondarily
causes systemic metabolic impairment in skeletal muscles and cardiomyocytes. The …
causes systemic metabolic impairment in skeletal muscles and cardiomyocytes. The …
Mechanisms of myofibre death in muscular dystrophies: the emergence of the regulated forms of necrosis in myology
M Bencze - International Journal of Molecular Sciences, 2022 - mdpi.com
Myofibre necrosis is a central pathogenic process in muscular dystrophies (MD). As post-
lesional regeneration cannot fully compensate for chronic myofibre loss, interstitial tissue …
lesional regeneration cannot fully compensate for chronic myofibre loss, interstitial tissue …
Analysis of mitochondrial function, structure, and intracellular organization in situ in cardiomyocytes and skeletal muscles
AV Kuznetsov, S Javadov, R Margreiter… - International Journal of …, 2022 - mdpi.com
Analysis of the function, structure, and intracellular organization of mitochondria is important
for elucidating energy metabolism and intracellular energy transfer. In addition, basic and …
for elucidating energy metabolism and intracellular energy transfer. In addition, basic and …
Mitochondria and Reactive Oxygen Species: The Therapeutic Balance of Powers for Duchenne Muscular Dystrophy
SR Casati, D Cervia, P Roux-Biejat, C Moscheni… - Cells, 2024 - mdpi.com
Duchenne muscular dystrophy (DMD) is a genetic progressive muscle-wasting disorder that
leads to rapid loss of mobility and premature death. The absence of functional dystrophin in …
leads to rapid loss of mobility and premature death. The absence of functional dystrophin in …