Acetylcholinesterase inhibitors (ChEI) are the global standard of care for the symptomatic
treatment of Alzheimer's disease (AD) and show significant positive effects in …

Dementia with Lewy bodies (DLB) is clinically defined by the presence of visual
hallucinations, fluctuations, rapid eye movement (REM) sleep behavioral disorder, and …

Abstract The endosome-associated GTPase Rab5 is a central player in the molecular
mechanisms leading to degeneration of basal forebrain cholinergic neurons (BFCN), a long …

Patients who have dementia with Lewy bodies and Alzheimer's disease show early
degeneration of the cholinergic nucleus basalis of Meynert. However, how white matter …

Mild cognitive impairment with the core clinical features of dementia with Lewy bodies is
recognized as a prodromal stage of dementia with Lewy bodies. Although grey matter …

Introduction Operationalized research criteria for mild cognitive impairment with Lewy
bodies (MCI‐LB) were published in 2020. The aim of this systematic review and meta …

Background and Objectives In a proportion of patients, dementia with Lewy bodies (DLB) is
associated with Alzheimer disease (AD) copathology, which is linked to accelerated …

INTRODUCTION Degeneration of cortical cholinergic projections from the nucleus basalis of
Meynert (NBM) is characteristic of dementia with Lewy bodies (DLB) and Alzheimer's …

Previous resting-state fMRI studies in dementia with Lewy bodies have described changes
in functional connectivity in networks related to cognition, motor function, and attention as …

Background: Dementia with Lewy bodies (DLB) is a type of dementia often diagnosed in
older patients. Since its initial symptoms range from delirium to psychiatric and cognitive …