Role of prenatal hypoxia in brain development, cognitive functions, and neurodegeneration

NN Nalivaeva, AJ Turner, IA Zhuravin - Frontiers in neuroscience, 2018 - frontiersin.org
This review focuses on the role of prenatal hypoxia in the development of brain functions in
the postnatal period and subsequent increased risk of neurodegenerative disorders in later …

Blood–brain-barriers in aging and in Alzheimer's disease

F Marques, JC Sousa, N Sousa, JA Palha - Molecular neurodegeneration, 2013 - Springer
The aging process correlates with a progressive failure in the normal cellular and organ
functioning; these alterations are aggravated in Alzheimer's disease (AD). In both aging and …

Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice

J Zhao, W Bi, S Xiao, X Lan, X Cheng, J Zhang, D Lu… - Scientific reports, 2019 - nature.com
In this study, we investigated lipopolysaccharide (LPS)-induced cognitive impairment and
neuroinflammation in C57BL/6J mice by using behavioral tests, immunofluorescence …

In silico molecular docking analysis of karanjin against alzheimer's and parkinson's diseases as a potential natural lead molecule for new drug design, development …

C Gnanaraj, M Sekar, S Fuloria, SS Swain, SH Gan… - Molecules, 2022 - mdpi.com
Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
that have emerged as among the serious health problems of the 21st century. The …

A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognitive function in old mice

A Bilkei-Gorzo, O Albayram, A Draffehn, K Michel… - Nature medicine, 2017 - nature.com
The balance between detrimental, pro-aging, often stochastic processes and counteracting
homeostatic mechanisms largely determines the progression of aging. There is substantial …

Dietary and supplemental long-chain omega-3 fatty acids as moderators of cognitive impairment and Alzheimer's disease

AHR Wood, HF Chappell, MA Zulyniak - European journal of nutrition, 2022 - Springer
Purpose There is an ever-growing body of literature examining the relationship between
dietary omega-3 polyunsaturated fatty acids (ω3 PUFAs) and cerebral structure and function …

Primary hypothyroidism and Alzheimer's Disease: a tale of two

FH AlAnazi, HM Al-Kuraishy, A Alexiou… - Cellular and Molecular …, 2023 - Springer
Hypothyroidism (HPT) HPT could be a risk factor for the development and progression of
Alzheimer's disease (AD). In addition, progressive neurodegeneration in AD may affect the …

A narrative review of the role of transthyretin in health and disease

MA Liz, T Coelho, V Bellotti, MI Fernandez-Arias… - Neurology and …, 2020 - Springer
Transthyretin (TTR) is a tetrameric transport protein highly conserved through vertebrate
evolution and synthesized in the liver, choroid plexus, and retinal pigment epithelium. TTR …

The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus

EM Schwarz, PK Korhonen, BE Campbell, ND Young… - Genome biology, 2013 - Springer
Background The barber's pole worm, Haemonchus contortus, is one of the most
economically important parasites of small ruminants worldwide. Although this parasite can …

Cross-interactions between the Alzheimer disease amyloid-β peptide and other amyloid proteins: a further aspect of the amyloid cascade hypothesis

J Luo, SKTS Wärmländer, A Gräslund… - Journal of Biological …, 2016 - ASBMB
Many protein folding diseases are intimately associated with accumulation of amyloid
aggregates. The amyloid materials formed by different proteins/peptides share many …