Combined whole cell wall analysis and streamlined in silico carbohydrate-active enzyme discovery to improve biocatalytic conversion of agricultural crop residues

JP Tingley, KE Low, X Xing, DW Abbott - Biotechnology for biofuels, 2021 - Springer
The production of biofuels as an efficient source of renewable energy has received
considerable attention due to increasing energy demands and regulatory incentives to …

Development of a spore-based mucosal vaccine against the bovine respiratory pathogen Mannheimia haemolytica

MS Uddin, JO Guluarte, DW Abbott, GD Inglis… - Scientific Reports, 2023 - nature.com
Bovine respiratory disease (BRD) is a significant health issue in the North American feedlot
industry, causing substantial financial losses due to morbidity and mortality. A lack of …

Application of transcriptomics to compare the carbohydrate active enzymes that are expressed by diverse genera of anaerobic fungi to degrade plant cell wall …

RJ Gruninger, TTM Nguyen, ID Reid, JL Yanke… - Frontiers in …, 2018 - frontiersin.org
The efficiency with which the anaerobic fungi (phylum Neocallimastigomycota) degrade
plant biomass is well-recognized and in recent years has received renewed interest. To …

SACCHARIS: an automated pipeline to streamline discovery of carbohydrate active enzyme activities within polyspecific families and de novo sequence datasets

DR Jones, D Thomas, N Alger, A Ghavidel… - Biotechnology for …, 2018 - Springer
Background Deposition of new genetic sequences in online databases is expanding at an
unprecedented rate. As a result, sequence identification continues to outpace functional …

Bifidobacterial GH146 β-l-arabinofuranosidase for the removal of β1,3-l-arabinofuranosides on plant glycans

K Fujita, H Tsunomachi, P Lixia, S Maruyama… - Applied Microbiology …, 2024 - Springer
Abstract l-Arabinofuranosides with β-linkages are present in several plant molecules, such
as arabinogalactan proteins (AGPs), extensin, arabinan, and rhamnogalacturonan-II. We …

Characterization of the dynamic changes of ruminal microbiota colonizing citrus pomace waste during rumen incubation for volatile fatty acid production

S Yu, L Li, H Zhao, Y Tu, M Liu, L Jiang… - Microbiology …, 2023 - Am Soc Microbiol
Rumen microorganisms are promising for efficient bioconversion of lignocellulosic wastes to
biofuels and industrially relevant products. Investigating the dynamic changes of the rumen …

Biochemical unravelling of the endoxylanase activity in a bifunctional GH39 enzyme cloned and expressed from thermophilic Geobacillus sp. WSUCF1

R Rai, D Samanta, KM Goh, BS Chadha… - International Journal of …, 2024 - Elsevier
The glycoside hydrolase family 39 (GH39) proteins are renowned for their extremophilic and
multifunctional enzymatic properties, yet the molecular mechanisms underpinning these …

Open prediction of polysaccharide utilisation loci (PUL) in 5414 public Bacteroidetes genomes using PULpy

RD Stewart, MD Auffret, R Roehe, M Watson - BioRxiv, 2018 - biorxiv.org
Polysaccharide utilisation loci (PUL) are regions within bacterial genomes that encode all
the necessary machinery for the cleavage of particular carbohydrates. For the Bacteroidetes …

Novel 3-O-α-d-Galactosyl-α-l-Arabinofuranosidase for the Assimilation of Gum Arabic Arabinogalactan Protein in Bifidobacterium longum subsp. longum

Y Sasaki, A Horigome, T Odamaki, JZ Xiao… - Applied and …, 2021 - Am Soc Microbiol
Gum arabic arabinogalactan (AG) protein (AGP) is a unique dietary fiber that is degraded
and assimilated by only specific strains of Bifidobacterium longum subsp. longum. Here, we …

Importance of accessory enzymes in hemicellulose degradation

V Puchart, K Šuchová, P Biely - Polysaccharide-Degrading Biocatalysts, 2023 - Elsevier
This chapter reviews microbial enzymes degrading two major plant hemicelluloses, xylan
and β-mannan. The main chains of these two polysaccharides are built of β-1, 4 …