One of the most influential books ever to have been written in the field of chemistry is e
Nature of the Chemical Bond by Linus Pauling [1], the first edition of which was published in …

The intracellular transport of organelles along an axon is crucial for the maintenance and
function of a neuron. Anterograde axonal transport has a role in supplying proteins and …

Cytoplasmic dynein-1 binds dynactin and cargo adaptor proteins to form a transport
machine capable of long-distance processive movement along microtubules. However, it is …

The endocytic pathway is essential for processes that define how cells interact with their
environment, including receptor signalling, cell adhesion and migration, pathogen entry …

Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …

Cytoplasmic dynein, a member of the AAA (ATPases Associated with diverse cellular
Activities) family of proteins, drives the processive movement of numerous intracellular …

A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

Myosins are a large family of actin-based cytoskeletal motors that use energy derived from
ATP hydrolysis to generate movement and force. Myosins of classes II, V and VI have …

Intracellular vesicle trafficking is the fundamental process to maintain the homeostasis of
membrane-enclosed organelles in eukaryotic cells. These organelles transport cargo from …

As the prototype of unconventional myosin motor family, myosin Va (MyoVa) transport
cellular cargos along actin filaments in diverse cellular processes. The off-duty MyoVa …