In 1994, Ye and McKervey published a paper in Chemical Reviews entitled “Organic
Synthesis with α-Diazocarbonyl Compounds”. 1 Our intention then was to draw attention to …

New Directions in Ketene Chemistry: The Land of Opportunity - Allen - 2012 - European
Journal of Organic Chemistry - Wiley Online Library Skip to Article Content Skip to Article …

Highly diastereoselective synthesis of some novel benzothiazole-substituted β-lactam
hybrids was achieved starting from (benzo [d] thiazol-2-yl) phenol as an available precursor …

A series of novel bis (indolyl) methane-β-lactam hybrids has been efficiently synthesized by
a [2+ 2]-cycloaddition reaction of imines 5a-c with ketenes derived from substituted acetic …

Ketenes are typically highly reactive compounds, undergoing addition reactions with
electrophiles and nucleophiles as well as being subjected to [2+ 2] cycloadditions with …

Recent years have witnessed significant advancement in cycloaddition and cyclization
strategies for the synthesis of monocyclic β-lactams. Cycloadditions include the Staudinger's …

Highly stereoselective synthesis of 3-pyrrole substituted β-lactams is accomplished. The first
step involves the synthesis of 3-phthalimido substituted β-lactams following Staudinger …

We report the synthesis of some novel β-lactam hybrids of 2-mercaptobenzothiazole and
benzoquinoline. These compounds were synthesized by a [2+ 2]-cycloaddition reaction of …

This article reports for the first time the synthesis of some novel β-lactam morpholino-1, 3, 5-
triazine hybrids by a [2+ 2]-cycloaddition reaction of imines 7a–c, 9a–c and 11 with ketenes …

Highly stereoselective synthesis of saccharin derivatives containing functionalized 2-
azetidinone moiety was achieved starting from saccharin as an available precursor. The …