Anthrax is caused by the spore-forming, gram-positive bacterium Bacillus anthracis. The
bacterium's major virulence factors are (a) the anthrax toxins and (b) an antiphagocytic …

The pathophysiological effects resulting from many bacterial diseases are caused by
exotoxins released by the bacteria. Bacillus anthracis, a spore-forming bacterium, is such a …

Anthrax lethal toxin (LT) and edema toxin (ET) are the major virulence factors of anthrax and
can replicate the lethality and symptoms associated with the disease. This review provides …

Anthrax has been feared for its high mortality in animals and humans for centuries. The
etiologic agent is considered a potentially devastating bioweapon, and since 1876―when …

Anthrax is a severe, although rather rare, infectious disease that is caused by the Gram-
positive, spore-forming bacterium Bacillus anthracis. The infectious form is the spore and the …

Anthrax toxin, a major virulence factor of Bacillus anthracis, gains entry into target cells by
binding to either of 2 von Willebrand factor A domain-containing proteins, tumor endothelium …

Bacillus anthracis, the causative agent of anthrax disease, is lethal owing to the actions of
two exotoxins: anthrax lethal toxin (LT) and oedema toxin (ET). The key tissue targets …

Bacterial toxins are virulence factors that manipulate host cell functions and take over the
control of vital processes of living organisms to favor microbial infection. Some toxins directly …

Bacterial products can act on neurons to alter signaling and function. In the present study,
we found that dorsal root ganglion (DRG) sensory neurons are enriched for ANTXR2, the …

Infectious microbes face an unwelcoming environment in their mammalian hosts, which
have evolved elaborate multicelluar systems for recognition and elimination of invading …