The calcium pump (aka Ca 2+-ATPase or SERCA) is a membrane transport protein
ubiquitously found in the endoplasmic reticulum (ER) of all eukaryotic cells. As a calcium …

The sodium/potassium-ATPase (NKA) is the enzyme that establishes gradients of sodium
and potassium across the plasma membrane. NKA activity is tightly regulated for different …

P-type ATPases are ATP-powered ion pumps that establish ion concentration gradients
across biological membranes, and are distinct from other ATPases in that the reaction cycle …

The sarco (endo) plasmic reticulum calcium ATPase (SERCA) is regulated in a tissue-
dependent manner via interaction with the short integral membrane proteins …

The physicochemical properties of the lipid bilayer shape the structure and topology of
membrane proteins and regulate their biological function. Here, we investigated the …

Calcium is a universal second messenger involved in diverse cellular processes, including
excitation-contraction coupling in muscle. The contraction and relaxation of cardiac muscle …

The transport activity of the sarco (endo) plasmic reticulum calcium ATPase (SERCA) in
cardiac myocytes is modulated by an inhibitory interaction with a transmembrane peptide …

Regulation of the SERCA calcium pump by phospholamban (PLB) is largely due to
interactions between their respective transmembrane domains. In spite of numerous …

Intracellular calcium signaling is essential for all kingdoms of life. An important part of this
process is the sarco-endoplasmic reticulum Ca2+-ATPase (SERCA), which maintains the …

Over the years, membrane-soluble peptides have provided a convenient model system to
investigate the folding and assembly of integral membrane proteins. Recent advances in …