In rapid sequence induction of anaesthesia in the emergency setting in shocked or
hypotensive patients (eg ruptured abdominal aortic aneurysm, polytrauma or septic shock) …

Animal models of critical illness are vital in biomedical research. They provide possibilities
for the investigation of pathophysiological processes that may not otherwise be possible in …

Background Dexmedetomidine is an alpha2‐adrenergic agonist used for sedation and
analgesia in children. We previously showed that dexmedetomidine depresses sinus and …

Background Anaesthetic induction occurs at higher plasma drug concentrations than
emergence in animal studies. Some studies find evidence for such anaesthetic hysteresis in …

Introduction The availability of medications such as remifentanyl and propofol has made
anesthesiologists feel the need to understand the basics of total intravenous anesthesia …

6 Entropy Page 1 173 6 Entropy Jennifer M. Yentes CONTENTS What is Entropy? ....................................................................................................
174 Entropy Measures for Time Series Data ................................................................ 178 …

Background Previous work on the electroencephalographic (EEG) effects of anaesthetic
doses of ketamine has identified a characteristic signature of increased high frequency (beta …

Desde hace ya algunos años, la ketamina ha sido usada como analgésico, tanto en el
intraoperatorio como en el postoperatorio en diversos tipos de intervenciones quirúrgicas; …

Editorial Views humans suggest that there is either no change or some shift to higher
frequencies. When given alone, ketamine causes a simultaneous increase in …

It is a well established clinical observation that, at low concentrations, most anesthetic
agents produce a surge in brain activity that occurs around the time of loss of …