In recent years, exploration of the developing brain has become a major focus for
researchers and clinicians in an attempt to understand what allows children to acquire …

Creatine metabolism is an important component of cellular energy homeostasis. Via the
creatine kinase circuit, creatine derived from our diet or synthesized endogenously provides …

Background Preterm infants are frequently exposed to intermittent hypoxia (IH) associated
with apnea and periodic breathing that may result in inflammation and brain injury that later …

Cognitive and behavioral disabilities in preterm infants, even without obvious brain injury on
conventional neuroimaging, underscores a critical need to identify the subtle underlying …

The inhibitory neurotransmitter γ-Aminobutyric acid (GABA) plays a crucial role in cortical
development. Therefore, characterizing changes in GABA levels during development has …

Background Physiological adaptations during pregnancy alter nutrient and energy
metabolism. Creatine may be important for maintaining cellular energy homeostasis …

Background Executive function deficits in children born very preterm (VPT) have been linked
to anatomical abnormalities in white matter and subcortical brain structures. This study …

This article reviews the most commonly used modern sequences designed to confront the
two major challenges of in vivo magnetic resonance spectroscopy (MRS): spatial …

Congenital heart disease, particularly cyanotic congenital heart disease (CCHD), may lead
to a neurodevelopmental delay through central nervous system injury, more unstable central …

Background Preterm infants are at risk of neurodevelopmental impairments. At present,
proton magnetic resonance spectroscopy (1H-MRS) is currently used to evaluate brain …