Background: With advances in sequencing technology and decreasing costs, the number of
phage genomes that have been sequenced has increased markedly in the past decade …

Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of
multidrug-resistant bacterial infections and other applications due to their unparalleled …

Antimicrobial resistance (AMR) is a major problem globally. The main bacterial organisms
associated with urinary tract infection (UTI) associated sepsis are E. coli and Klebsiella …

Background Viruses are the most abundant biological entities on Earth, known to be crucial
components of microbial ecosystems. However, there is little information on the viral …

The aim of this study was to gain further insight into the diversity of Escherichia coli phages
followed by enhanced work on taxonomic issues in that field. Therefore, we present the …

Introduction: Klebsiella is a clinically important pathogen causing a variety of antimicrobial
resistant infections in both community and nosocomial settings, particularly pneumonia …

Escherichia phage N4 was isolated in 1966 in Italy and has remained a genomic orphan for
a long time. It encodes an extremely large virion-associated RNA polymerase unique for …

Viral metagenomics has fuelled a rapid change in our understanding of global viral diversity
and ecology. Long-read sequencing and hybrid assembly approaches that combine long …

With the recent rise in interest in using lytic bacteriophages as therapeutic agents, there is
an urgent requirement to understand their fundamental biology to enable the engineering of …

Aims This study describes the physicochemical and genomic characterization of phage
vB_Vc_SrVc9 and its potential for phage therapy application against a pathogenic Vibrio …