Fatty acids as antibiofilm and antivirulence agents

P Kumar, JH Lee, H Beyenal, J Lee - Trends in microbiology, 2020 - cell.com
Fatty acids (FAs) have emerged as a potential alternative to conventional antibiotics. Since
many microbes respond differently to a variety of natural and synthetic FAs, substantial …

The potential of fatty acids and their derivatives as antifungal agents: A review

A Guimarães, A Venâncio - Toxins, 2022 - mdpi.com
Fungal contamination presents several problems: in humans, health issues arise from
infections with opportunistic filamentous fungi and yeast, while in food, fungi cause spoilage …

Antibiofilm and antifungal activities of medium‐chain fatty acids against Candida albicans via mimicking of the quorum‐sensing molecule farnesol

JH Lee, YG Kim, SK Khadke, J Lee - Microbial Biotechnology, 2021 - Wiley Online Library
Candida biofilms are tolerant to conventional antifungal therapeutics and the host immune
system. The transition of yeast cells to hyphae is considered a key step in C. albicans biofilm …

Cuminaldehyde in cumin essential oils prevents the growth and aflatoxin B1 biosynthesis of Aspergillus flavus in peanuts

D Xu, M Wei, S Peng, H Mo, L Huang, L Yao, L Hu - Food Control, 2021 - Elsevier
The contamination of food with Aspergillus flavus has caused serious economic losses and
posed a great threat to human and animal health. Cumin, a condiment and flavoring in many …

Extracellular vesicles regulate biofilm formation and yeast-to-hypha differentiation in Candida albicans

L Honorato, JFD de Araujo, CC Ellis, AC Piffer… - MBio, 2022 - Am Soc Microbiol
In this study, we investigated the influence of fungal extracellular vesicles (EVs) during
biofilm formation and morphogenesis in Candida albicans. Using crystal violet staining and …

Antibiofilm and antivirulence efficacy of myrtenol enhances the antibiotic susceptibility of Acinetobacter baumannii

A Selvaraj, A Valliammai, C Sivasankar, M Suba… - Scientific reports, 2020 - nature.com
Acinetobacter baumannii (AB) is rising as a human pathogen of critical priority worldwide as
it is the leading cause of chronic opportunistic infections in healthcare settings and the …

Palmitic Acid Inhibits the Virulence Factors of Candida tropicalis: Biofilms, Cell Surface Hydrophobicity, Ergosterol Biosynthesis, and Enzymatic Activity

KG Prasath, H Tharani, MS Kumar… - Frontiers in …, 2020 - frontiersin.org
Biofilm is the fortitude of Candida species infections which eventually causes candidiasis in
human. C. tropicalis is one of the predominant Candida species commonly found in systemic …

Inhibition of polymicrobial biofilm formation by saw palmetto oil, lauric acid and myristic acid

YG Kim, JH Lee, S Park, S Kim, J Lee - Microbial biotechnology, 2022 - Wiley Online Library
Biofilms are communities of bacteria, fungi or yeasts that form on diverse biotic or abiotic
surfaces, and play important roles in pathogenesis and drug resistance. A generic saw …

[HTML][HTML] Pentadecanoic acid against Candida albicans-Klebsiella pneumoniae biofilm: Towards the development of an anti-biofilm coating to prevent polymicrobial …

E Galdiero, A Ricciardelli, C D'Angelo… - Research in …, 2021 - Elsevier
The ability to form biofilms is a common feature of microorganisms, which can colonize a
variety of surfaces, such as host tissues and medical devices, resulting in infections highly …

Piperine Impedes Biofilm Formation and Hyphal Morphogenesis of Candida albicans

A Priya, SK Pandian - Frontiers in microbiology, 2020 - frontiersin.org
Candida albicans is the primary etiological agent associated with the pathogenesis of
candidiasis. Unrestricted growth of C. albicans in the oral cavity may lead to oral candidiasis …