A review on the functional characteristics of the c-Myeloproliferative Leukaemia (c-MPL) gene and its isoforms
The c-MPL-TPO axis regulates hematopoiesis by activating various signalling cascades,
including JAK/STAT, MAPK/ERK, and PIK3/AKT. Here, we have summarized how TPO is …
including JAK/STAT, MAPK/ERK, and PIK3/AKT. Here, we have summarized how TPO is …
[HTML][HTML] RNA splicing regulator EIF3D regulates the tumor microenvironment through immunogene-related alternative splicing in head and neck squamous cell …
D Lu, M Mihoayi, Y Ablikim, A Arikin - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Study finds that eukaryotic translation initiation factor 3 subunit D (EIF3D) may play an
important role in aberrant alternative splicing (AS) events in tumors. AS possesses a pivotal …
important role in aberrant alternative splicing (AS) events in tumors. AS possesses a pivotal …
METTL14 reverses liver fibrosis by inhibiting NOVA2 through an m6A-YTHDF2–dependent mechanism
X Hou, Y Li, J Song, L Peng, W Zhang… - Hepatology …, 2023 - journals.lww.com
Background: N 6-methyladenosine (m 6 A), the most prevalent internal RNA modification in
eukaryotic cells, is dynamically regulated in response to a wide range of physiological and …
eukaryotic cells, is dynamically regulated in response to a wide range of physiological and …
Advancements in Myeloid Leukemia Treatment: A Comprehensive Update
This comprehensive update explores the recent advancements in the treatment landscape
of myeloid leukemia. Myeloid leukemia, a heterogeneous group of hematological …
of myeloid leukemia. Myeloid leukemia, a heterogeneous group of hematological …