Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets

P Asgharian, AP Tazekand, K Hosseini… - Cancer cell …, 2022 - Springer
Over the past few years, the cancer-related disease has had a high mortality rate and
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …

Rutin: A flavonoid as an effective sensitizer for anticancer therapy; insights into multifaceted mechanisms and applicability for combination therapy

A Satari, S Ghasemi, S Habtemariam… - Evidence‐Based …, 2021 - Wiley Online Library
Rutin is a unique antioxidant flavonoid that is mainly found in fruit, vegetables, cereals, and
many other plant‐based human diets. This review aims to highlight the in vitro anticancer …

Molecular mechanisms of anticancer effect of rutin

A Imani, N Maleki, S Bohlouli… - Phytotherapy …, 2021 - Wiley Online Library
Because of the extensive biological functions of natural substances such as bioflavonoids,
and their high safety and low costs, they could have high priority application in the health …

Targeting multiple signaling pathways in cancer: The rutin therapeutic approach

Z Nouri, S Fakhri, K Nouri, CE Wallace, MH Farzaei… - Cancers, 2020 - mdpi.com
Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …

The anticancer potential of the dietary polyphenol rutin: Current status, challenges, and perspectives

AK Farha, RY Gan, HB Li, DT Wu… - Critical Reviews in …, 2022 - Taylor & Francis
Rutin is one of the most common dietary polyphenols found in vegetables, fruits, and other
plants. It is metabolized by the mammalian gut microbiota and absorbed from the intestines …

An investigation into green synthesis of Ru template gold nanoparticles and the in vitro photothermal effect on the MCF-7 human breast cancer cell line

L Shabani, SR Kasaee, S Chelliapan, M Abbasi… - Applied Physics A, 2023 - Springer
In recent years, laser photothermal therapy of cancers, as a new adjuvant treatment, has
attracted a lot of attention. Nanoparticles have been applied to increase the effect of …

[HTML][HTML] Baicalin; a promising chemopreventive agent, enhances the antitumor effect of 5-FU against breast cancer and inhibits tumor growth and angiogenesis in …

NH Shehatta, TM Okda, GA Omran… - Biomedicine & …, 2022 - Elsevier
Despite considerable advances in cancer treatment, chemotherapy remains a cornerstone
in breast cancer therapy. Therefore, reducing chemoresistance and adverse effects of …

Comparative Assessment of the Antioxidant and Anticancer Activities of Plicosepalus acacia and Plicosepalus curviflorus: Metabolomic Profiling and In Silico Studies

EE Eltamany, MS Goda, MS Nafie, AM Abu-Elsaoud… - Antioxidants, 2022 - mdpi.com
This study presents a comparison between two mistletoe plants—P. acacia and P.
curviflorus—regarding their total phenolic contents and antioxidant and anticancer activities …

Insights into molecular docking and dynamics to reveal therapeutic potential of natural compounds against P53 protein

BA Malla, A Ali, I Maqbool, NA Dar… - Journal of …, 2023 - Taylor & Francis
P53 is eminent tumour suppressor protein that plays a prominent role in cell cycle arrest,
DNA repair, senescence, differentiation and initiation of apoptosis. P53 is an attractive drug …

Synergistic therapy with tangeretin and 5-fluorouracil accelerates the ROS/JNK mediated apoptotic pathway in human colorectal cancer cell

DK Dey, SN Chang, Y Vadlamudi, JG Park… - Food and Chemical …, 2020 - Elsevier
Synergistic therapy is emerging as a promising strategy for improving the chemotherapeutic
efficacy of anticancer drugs. Addition of adjuvants with standard anticancer drugs has shown …