Esophageal squamous cell carcinoma (ESCC) accounts for about 90% of the 456,000
incident esophageal cancers each year. Regions of high incidence include Eastern to …

In this article, we reviewed the association between alcohol drinking and head and neck
cancer (HNC) and its subsites, using the available literature. Alcohol drinking is an …

Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

Bipolar disorder (BD) is a common and highly heritable mental illness and genome-wide
association studies (GWAS) have robustly identified the first common genetic variants …

Reactive aldehydes are common carcinogens. They are also by-products of several
metabolic pathways and, without enzymatic catabolism, may accumulate and cause DNA …

We conducted a genome-wide association study of oral cavity and pharyngeal cancer in
6,034 cases and 6,585 controls from Europe, North America and South America. We …

Tobacco use and alcohol consumption are the main risk factors associated with head and
neck squamous cell carcinoma (SCC) development due to their cytotoxic and mutagenic …

ABSTRACT The International Agency for Research on Cancer (IARC) and the US National
Cancer Institute (NCI) have initiated a series of cancer-focused seminars [Scelo G, Hofmann …

Aldehyde dehydrogenases (ALDHs), as essential regulators of aldehyde metabolism in the
human body, protect organisms from damage induced by active aldehydes. Given their roles …

We conducted a genome-wide association study (GWAS) and a genome-wide gene-
environment interaction analysis of esophageal squamous-cell carcinoma (ESCC) in 2,031 …