Cancer and climate change

RA Hiatt, N Beyeler - The Lancet Oncology, 2020 - thelancet.com
The acute impact of climate change on human health is receiving increased attention, but
little is known or appreciated about the effect of climate change on chronic diseases …

Roles of miRNA and IncRNA in triple-negative breast cancer

J Xu, K Wu, Q Jia, X Ding - Journal of Zhejiang University-science b, 2020 - Springer
Triple-negative breast cancer (TNBC) is currently the most malignant subtype of breast
cancer without effective targeted therapies, which makes its pathogenesis an important …

Bisphenol A replacement chemicals, BPF and BPS, induce protumorigenic changes in human mammary gland organoid morphology and proteome

J Winkler, P Liu, K Phong, JH Hinrichs… - Proceedings of the …, 2022 - National Acad Sciences
Environmental chemicals such as bisphenol A (BPA) are thought to contribute to
carcinogenesis through their endocrine-disrupting properties. Due to accumulating evidence …

Omics-based investigations of breast cancer

AN Neagu, D Whitham, P Bruno, H Morrissiey… - Molecules, 2023 - mdpi.com
Breast cancer (BC) is characterized by an extensive genotypic and phenotypic
heterogeneity. In-depth investigations into the molecular bases of BC phenotypes …

[HTML][HTML] Breast cancers, mammary stem cells, and cancer stem cells, characteristics, and hypotheses

S Taurin, H Alkhalifa - Neoplasia, 2020 - Elsevier
The cellular heterogeneity of breast cancers still represents a major therapeutic challenge.
The latest genomic studies have classified breast cancers in distinct clusters to inform the …

Interplay between Estrogen, Kynurenine, and AHR Pathways: An immunosuppressive axis with therapeutic potential for breast cancer treatment

JHL Pacheco, G Elizondo - Biochemical Pharmacology, 2023 - Elsevier
Breast cancer is one of the most common malignancies among women worldwide. Estrogen
exposure via endogenous and exogenous sources during a lifetime, together with …

Childhood socioeconomic status and menarche: a prospective study

RA Hiatt, SL Stewart, J Deardorff, E Danial… - Journal of Adolescent …, 2021 - Elsevier
Purpose The relationship between socioeconomic status (SES) and menarche has
implications for understanding social level influences on early life development and adult …

Environmental mixtures and breast cancer: identifying co-exposure patterns between understudied vs breast cancer-associated chemicals using chemical inventory …

LE Koval, KL Dionisio, KP Friedman… - Journal of exposure …, 2022 - nature.com
Background Although evidence linking environmental chemicals to breast cancer is
growing, mixtures-based exposure evaluations are lacking. Objective This study aimed to …

Onco-Breastomics: An Eco-Evo-Devo Holistic Approach

AN Neagu, D Whitham, P Bruno, A Arshad… - International Journal of …, 2024 - mdpi.com
Known as a diverse collection of neoplastic diseases, breast cancer (BC) can be
hyperbolically characterized as a dynamic pseudo-organ, a living organism able to build a …

Suppression of ferroportin expression by cadmium stimulates proliferation, EMT, and migration in triple-negative breast cancer cells

Z Shan, Z Wei, ZA Shaikh - Toxicology and applied pharmacology, 2018 - Elsevier
Cadmium (Cd) has been linked to a variety of cancers, including breast cancer; however, the
molecular mechanism of its carcinogenic activity is not fully understood. To this end, the …