Advanced nitric oxide generating nanomedicine for therapeutic applications
Nitric oxide (NO), a gaseous transmitter extensively present in the human body, regulates
vascular relaxation, immune response, inflammation, neurotransmission, and other crucial …
vascular relaxation, immune response, inflammation, neurotransmission, and other crucial …
Recent advances in the development of nitric oxide-releasing biomaterials and their application potentials in chronic wound healing
M Wu, Z Lu, K Wu, C Nam, L Zhang… - Journal of Materials …, 2021 - pubs.rsc.org
Chronic wounds, such as pressure ulcers, vascular ulcers and diabetic foot ulcers (DFUs),
often stay in a state of pathological inflammation and suffer from persistent infection, excess …
often stay in a state of pathological inflammation and suffer from persistent infection, excess …
Opportunities for nitric oxide in potentiating cancer immunotherapy
Despite nearly 30 years of development and recent highlights of nitric oxide (NO) donors
and NO delivery systems in anticancer therapy, the limited understanding of exogenous …
and NO delivery systems in anticancer therapy, the limited understanding of exogenous …
Nitric oxide releasing nanomaterials for cardiovascular applications
TA Tabish, MJ Crabtree, HE Townley… - Basic to Translational …, 2024 - jacc.org
A central paradigm of cardiovascular homeostasis is that impaired nitric oxide (NO)
bioavailability results in a wide array of cardiovascular dysfunction including incompetent …
bioavailability results in a wide array of cardiovascular dysfunction including incompetent …
[HTML][HTML] Multi-biofunctional graphene oxide-enhanced poly-L-lactic acid composite nanofiber scaffolds for ovarian function recovery of transplanted-tissue
L Yan, L Wang, J Wu, Y Wu, X Zhu, Q Mei… - NPJ Regenerative …, 2022 - nature.com
In this study, we successfully constructed the new graphene oxide/poly-L-lactic acid
(GO/PLLA) nanofiber scaffolds with a hydrophilic surface and porous network structure that …
(GO/PLLA) nanofiber scaffolds with a hydrophilic surface and porous network structure that …
[HTML][HTML] Small molecules for great solutions: Can nitric oxide-releasing nanomaterials overcome drug resistance in chemotherapy?
Nitric oxide (NO) is an endogenous free radical that controls important physiological and
pathophysiological processes, including a role in cancer biology. NO can have a direct toxic …
pathophysiological processes, including a role in cancer biology. NO can have a direct toxic …
[HTML][HTML] Bimodal modulation of in vitro angiogenesis with photoactive polymer nanoparticles
Angiogenesis is a fundamental process in biology, given the pivotal role played by blood
vessels in providing oxygen and nutrients to tissues, thus ensuring cell survival. Moreover, it …
vessels in providing oxygen and nutrients to tissues, thus ensuring cell survival. Moreover, it …
Weibull β value for the discernment of drug release mechanism of PLGA particles
U de Jesús Martín-Camacho… - International Journal of …, 2023 - Elsevier
Mathematical models are used to characterize and optimize drug release in drug delivery
systems (DDS). One of the most widely used DDS is the poly (lactic-co-glycolic acid)(PLGA) …
systems (DDS). One of the most widely used DDS is the poly (lactic-co-glycolic acid)(PLGA) …
Nitric oxide and immune responses in cancer: Searching for new therapeutic strategies
A Sahebnasagh, F Saghafi, S Negintaji… - Current medicinal …, 2022 - ingentaconnect.com
In recent years, there has been an increasing interest in understanding the mysterious
functions of nitric oxide (NO) and how this pleiotropic signaling molecule contributes to …
functions of nitric oxide (NO) and how this pleiotropic signaling molecule contributes to …
[HTML][HTML] CX3CL1 (Fractalkine)-CX3CR1 Axis in Inflammation-Induced Angiogenesis and Tumorigenesis
D Szukiewicz - International journal of molecular sciences, 2024 - mdpi.com
The chemotactic cytokine fractalkine (FKN, chemokine CX3CL1) has unique properties
resulting from the combination of chemoattractants and adhesion molecules. The soluble …
resulting from the combination of chemoattractants and adhesion molecules. The soluble …