Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural Product …, 2015 - pubs.rsc.org
Covering: 2013. Previous review: Nat. Prod. Rep., 2014, 31, 160–258 This review covers the
literature published in 2013 for marine natural products (MNPs), with 982 citations (644 for …

[2+ 2]-Cycloaddition-derived cyclobutane natural products: structural diversity, sources, bioactivities, and biomimetic syntheses

P Yang, Q Jia, S Song, X Huang - Natural Product Reports, 2023 - pubs.rsc.org
Covering: up to the end of 2021 [2+ 2]-Type cyclobutane natural products are
biosynthetically derived from intermolecular [2+ 2] cycloaddition or intramolecular [2+ 2] …

Biomaterials and bioactive natural products from marine invertebrates: From basic research to innovative applications

G Romano, M Almeida, A Varela Coelho, A Cutignano… - Marine Drugs, 2022 - mdpi.com
Aquatic invertebrates are a major source of biomaterials and bioactive natural products that
can find applications as pharmaceutics, nutraceutics, cosmetics, antibiotics, antifouling …

Recent updates on development of protein-tyrosine phosphatase 1B inhibitors for treatment of diabetes, obesity and related disorders

S Singh, AS Grewal, R Grover, N Sharma, B Chopra… - Bioorganic …, 2022 - Elsevier
The aim of this review was to discuss an overview of type 2 diabetes; biology of PTP1B; role
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …

Marine pharmacology in 2012–2013: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral …

AMS Mayer, AD Rodríguez, O Taglialatela-Scafati… - Marine drugs, 2017 - mdpi.com
The peer-reviewed marine pharmacology literature from 2012 to 2013 was systematically
reviewed, consistent with the 1998–2011 reviews of this series. Marine pharmacology …

PTP1B inhibitors for type 2 diabetes treatment: a patent review (2011–2014)

AK Tamrakar, CK Maurya, AK Rai - Expert opinion on therapeutic …, 2014 - Taylor & Francis
Introduction: Protein tyrosine phosphatase 1B (PTP1B) plays an important role in the
negative regulation of insulin signal transduction pathway and has emerged as novel …

Uncommon Diterpenoids from the South China Sea Soft Coral Sinularia humilis and Their Stereochemistry

LL Sun, WS Li, J Li, HY Zhang, LG Yao… - The Journal of …, 2021 - ACS Publications
The chemical investigation of the South China Sea soft coral Sinularia humilis has resulted
in the isolation of a library of diverse diterpenoids, including four new cembranoids, namely …

Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review

YA Elkhawas, AM Elissawy, MS Elnaggar, NM Mostafa… - Marine drugs, 2020 - mdpi.com
One of the most widely distributed soft coral species, found especially in shallow waters of
the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus …

Sinusiaetone A, an Anti-inflammatory Norditerpenoid with a Bicyclo[11.3.0]hexadecane Nucleus from the Hainan Soft Coral Sinularia siaesensis

ZH Chen, WS Li, ZY Zhang, H Luo, JR Wang… - Organic …, 2021 - ACS Publications
A novel norditerpenoid, sinusiaetone A (1), featuring an uncommon bicyclo [11.3. 0]
hexadecane carbon skeleton, and four polyoxygenated cembranoids (2–5) were isolated …

Chemistry and bioactivity of secondary metabolites from South China Sea marine fauna and flora: Recent research advances and perspective

J Liu, Y Gu, M Su, Y Guo - Acta Pharmacologica Sinica, 2022 - nature.com
Marine organisms often produce a variety of metabolites with unique structures and diverse
biological activities that enable them to survive and struggle in the extremely challenging …