Purpose Because preapproval clinical trials typically exclude pregnant women, the evidence
on drug safety during pregnancy required to inform drug labeling must come from …

Background Whether the use of selective serotonin-reuptake inhibitors (SSRIs) and other
antidepressants during pregnancy is associated with an increased risk of congenital cardiac …

Background There has been concern that exposure to lithium early in pregnancy may be
associated with a marked increase in the risk of Ebstein's anomaly (a right ventricular …

OBJECTIVE: To report the prevalence of prescription opioid use and evaluate the trends in a
large cohort of Medicaid-enrolled pregnant women. METHODS: A cohort of pregnancies …

Importance The association between selective serotonin reuptake inhibitor (SSRI)
antidepressant use during pregnancy and risk of persistent pulmonary hypertension of the …

Objective: Given the increasing use and broadening of indications for use of antipsychotic
medications in the general population, as well as the paucity of information on the safety of …

Background Hydroxychloroquine is generally considered safe in pregnancy for the treatment
of rheumatic conditions, but studies have been too small to evaluate teratogenicity …

Background: When exposure is infrequent, propensity-score matching results in reduced
precision because it discards a large proportion of unexposed patients. To our knowledge …

Importance The lack of standards in methods to reduce bias for clinical algorithms presents
various challenges in providing reliable predictions and in addressing health disparities …

Importance Neurodevelopmental disorders are associated with poor health and social
outcomes. Population-based data on incidence, age at diagnosis, and demographic …