Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems

DA Subramanian, R Langer, G Traverso - Journal of nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …

Nanoparticles for oral delivery: Design, evaluation and state-of-the-art

AA Date, J Hanes, LM Ensign - Journal of Controlled Release, 2016 - Elsevier
The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …

Nanoencapsulation techniques for food bioactive components: a review

PN Ezhilarasi, P Karthik, N Chhanwal… - Food and bioprocess …, 2013 - Springer
The protection and controlled release of bioactive compounds at the right time and the right
place can be implemented by encapsulation. Nanoencapsulation remains to be the one of …

Application of different nanocarriers for encapsulation of curcumin

Z Rafiee, M Nejatian, M Daeihamed… - Critical reviews in food …, 2019 - Taylor & Francis
Curcumin is the main polyphenol of the curcuminoid class of turmeric, a well-known spice
belonging to the ginger family. In addition to its common applications like coloring and …

Curcumin nanoformulations: a future nanomedicine for cancer

MM Yallapu, M Jaggi, SC Chauhan - Drug discovery today, 2012 - Elsevier
Curcumin, a natural diphenolic compound derived from turmeric Curcuma longa, has proven
to be a modulator of intracellular signaling pathways that control cancer cell growth …

Mucoadhesive vs. mucopenetrating particulate drug delivery

K Netsomboon, A Bernkop-Schnürch - European Journal of Pharmaceutics …, 2016 - Elsevier
Mucus layer is a hydrophilic absorption barrier found in various regions of the body. The use
of particulate delivery systems showed potential in drug delivery to mucosal membranes by …

Nanotechnology for increased micronutrient bioavailability

IJ Joye, G Davidov-Pardo, DJ McClements - Trends in food science & …, 2014 - Elsevier
Highlights•Colloidal delivery systems for food applications are created using
nanotechnology.•Edible nanoparticles are made from surfactants, lipids, protein and/or …

Pectin coating improves physicochemical properties of caseinate/zein nanoparticles as oral delivery vehicles for curcumin

C Chang, T Wang, Q Hu, M Zhou, J Xue, Y Luo - Food Hydrocolloids, 2017 - Elsevier
In this study, pectin was applied as a carbohydrate-based coating to improve
physicochemical stability of sodium caseinate/zein (CZ) complex protein nanoparticles …

Curcumin

MLAD Lestari, G Indrayanto - Profiles of drug substances, excipients and …, 2014 - Elsevier
Curcumin and its two related compounds, that is, demethoxycurcumin and bis-
demethoxycurcumin (curcuminoids) are the main secondary metabolites of Curcuma longa …

Caseinate-zein-polysaccharide complex nanoparticles as potential oral delivery vehicles for curcumin: Effect of polysaccharide type and chemical cross-linking

C Chang, T Wang, Q Hu, Y Luo - Food Hydrocolloids, 2017 - Elsevier
The formation of protein-polysaccharide complex nanoparticles was investigated using
caseinate (NaCas), zein, and three polysaccharides, ie pectin, carboxymethyl cellulose …