[HTML][HTML] Atrial fibrillation: pathogenesis, predisposing factors, and genetics

M Sagris, EP Vardas, P Theofilis… - International journal of …, 2021 - mdpi.com
Atrial fibrillation (AF) is the most frequent arrhythmia managed in clinical practice, and it is
linked to an increased risk of death, stroke, and peripheral embolism. The Global Burden of …

[HTML][HTML] The vascular endothelium and coagulation: homeostasis, disease, and treatment, with a focus on the von willebrand factor and factors VIII and V

JAD Pablo-Moreno, LJ Serrano, L Revuelta… - International Journal of …, 2022 - mdpi.com
The vascular endothelium has several important functions, including hemostasis. The
homeostasis of hemostasis is based on a fine balance between procoagulant and …

[HTML][HTML] Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)

M Haffke, H Freitag, G Rudolf, M Seifert… - Journal of Translational …, 2022 - Springer
Background Fatigue, exertion intolerance and post-exertional malaise are among the most
frequent symptoms of Post-COVID Syndrome (PCS), with a subset of patients fulfilling …

Endothelial dysfunction in acute and long standing COVID− 19: A prospective cohort study

E Oikonomou, N Souvaliotis, S Lampsas, G Siasos… - Vascular …, 2022 - Elsevier
Abstract Background Coronavirus disease-19 (COVID-19) is implicated by active
endotheliitis, and cardiovascular morbidity. The long-COVID-19 syndrome implications in …

The Lung Microbiota Affects Pulmonary Inflammation and Oxidative Stress Induced by PM2.5 Exposure

S Wang, Q Zhou, Y Tian, X Hu - Environmental science & …, 2022 - ACS Publications
Fine particulate matter (PM2. 5) exposure causes respiratory diseases by inducing
inflammation and oxidative stress. However, the correlation between the pulmonary …

The impact of SGLT2 inhibitors on inflammation: A systematic review and meta-analysis of studies in rodents

P Theofilis, M Sagris, E Oikonomou… - International …, 2022 - Elsevier
Background Inhibition of sodium-glucose cotransporter-2 (SGLT2) has received remarkable
attention due to the beneficial effects observed in diabetes mellitus, heart failure, and kidney …

[HTML][HTML] Gut-derived metabolite, trimethylamine-N-oxide (TMAO) in cardio-metabolic diseases: detection, mechanism, and potential therapeutics

M Shanmugham, S Bellanger, CH Leo - Pharmaceuticals, 2023 - mdpi.com
Trimethylamine N-oxide (TMAO) is a biologically active gut microbiome-derived dietary
metabolite. Recent studies have shown that high circulating plasma TMAO levels are closely …

[HTML][HTML] Delayed graft function in kidney transplant: risk factors, consequences and prevention strategies

C Ponticelli, F Reggiani, G Moroni - Journal of personalized medicine, 2022 - mdpi.com
Background. Delayed graft function is a frequent complication of kidney transplantation that
requires dialysis in the first week posttransplant. Materials and Methods. We searched for …

[HTML][HTML] Inflammatory mediators of platelet activation: focus on atherosclerosis and COVID-19

P Theofilis, M Sagris, AS Antonopoulos… - International Journal of …, 2021 - mdpi.com
Background: Atherosclerotic cardiovascular diseases are characterized by a dysregulated
inflammatory and thrombotic state, leading to devastating complications with increased …

[HTML][HTML] The impact of cytokines in coronary atherosclerotic plaque: current therapeutic approaches

P Tsioufis, P Theofilis, K Tsioufis… - International Journal of …, 2022 - mdpi.com
Coronary atherosclerosis is a chronic pathological process that involves inflammation
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …