Serum uric acid level as a marker for mortality and acute kidney injury in patients with acute paraquat intoxication

JH Kim, HW Gil, JO Yang, EY Lee… - Nephrology Dialysis …, 2011 - academic.oup.com
Background. Paraquat (PQ) is a non-selective herbicide that generates reactive oxygen
species (ROS) in vivo. Uric acid emerged as a marker of oxidative stress and may enhance …

[HTML][HTML] Effects of rapamycin against paraquat-induced pulmonary fibrosis in mice

X Shao, M Li, C Luo, Y Wang, Y Lu, S Feng… - Journal of Zhejiang …, 2015 - ncbi.nlm.nih.gov
Background and aims: Ingestion of paraquat (PQ), a widely used herbicide, can cause
severe toxicity in humans, leading to a poor survival rate and prognosis. One of the main …

[HTML][HTML] Rapamycin increases CCN2 expression of lung fibroblasts via phosphoinositide 3-kinase

X Xu, H Dai, J Geng, X Wan, X Huang, F Li… - Laboratory …, 2015 - Elsevier
Excessive production of connective tissue growth factor (CTGF, CCN2) and increased motor
ability of the activated fibroblast phenotype contribute to the pathogenesis of idiopathic …

[HTML][HTML] Rapamycin reduces mortality in acute-stage paraquat-induced toxicity in zebrafish

N Feng, Z Bian, X Zhang, C Wang… - Singapore medical …, 2019 - ncbi.nlm.nih.gov
METHODS To determine the maximum nonlethal concentration (MNLC) and lethal
concentration 50 (LC50) of Rapa, zebrafish were treated at 2–5 days post fertilisation (dpf) …

Rapamycin regulates connective tissue growth factor expression of lung epithelial cells via phosphoinositide 3-kinase

X Xu, X Wan, J Geng, F Li, T Yang… - … Biology and Medicine, 2013 - journals.sagepub.com
The pathogenesis of idiopathic pulmonary fibrosis (IPF) remains largely unknown. It is
believed that IPF is mainly driven by activated alveolar epithelial cells that have a …

Tissue concentration of paraquat on day 32 after intoxication and failed bridge to transplantation by extracorporeal membrane oxygenation therapy

A Bertram, SS Haenel, J Hadem, MM Hoeper… - BMC Pharmacology and …, 2013 - Springer
Background Paraquat is a highly toxic herbicide, which not only leads to acute organ
damage, but also to pulmonary fibrosis. There are only anecdotal reports of rescue lung …

Effect of Capparis spinosa Fruit Hydroalcoholic Extract on Paraquat-Induced Pulmonary Fibrosis in the Rat

T Ostovar, S Rezaei Arablouydareh… - International Journal of …, 2023 - ijmcmed.org
Pulmonary fibrosis (PF) is a lethal inflammatory disease and there has been no effective
medication for this progressive disease up to now. Paraquat is commonly used in …

Características epidemiológicas e clínicas de vítimas intoxicadas pelo herbicida Paraquat no cone sul da Amazônia Legal-Brasil: Intoxicação pelo herbicida Paraquat

LP de Souza, C Vasconcellos… - … of Medicine and …, 2021 - iajmh.emnuvens.com.br
Objective: To analyze the epidemiological and clinical profile of victims intoxicated by the
herbicide Paraquat treated in the emergency of the Hospital Complex in the south of the …

[PDF][PDF] 百草枯应用现状及其对动物的毒性机制研究进展

张玉玲, 唐超智 - 河南师范大学学报(自然科学版), 2016 - htu.edu.cn
百草枯(PQ) 是世界上第二大除草剂, 自注册使用以来一直受到农业生产者的喜爱,
但多年使用PQ 已导致了越来越严重的公共健康问题. 之前的研究已对PQ 的呼吸 …

[PDF][PDF] Analysis of prognostic factors in patients with paraquat poisoning for better therapy regimen

Y Xu, Y Chen, J Le, Z Chen, H Wang, P Zhang, Y He… - Res Sq, 2020 - scholar.archive.org
Analysis of Prognostic Factors in Patients with Paraquat Poisoning for Better Therapy Regimen
Page 1 Page 1/19 Analysis of Prognostic Factors in Patients with Paraquat Poisoning for Better …